J 2005

Degradation of b-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26.

NAGATA, Yuji, Zbyněk PROKOP, Yukari SATO, Petr JEŘÁBEK, Ashawi KUMAR et. al.

Basic information

Original name

Degradation of b-Hexachlorocyclohexane by Haloalkane Dehalogenase LinB from Sphingomonas paucimobilis UT26.

Name in Czech

Degradace b-Hexachlorocyclohexanu haloalkan dehalogenázou LinB z bakterie Sphingomonas paucimobilis UT26.

Authors

NAGATA, Yuji (392 Japan), Zbyněk PROKOP (203 Czech Republic), Yukari SATO (392 Japan), Petr JEŘÁBEK (203 Czech Republic), Ashawi KUMAR (356 India), Yoshiyuhi OHTSUBO (392 Japan), Masataka TSUDA (392 Japan) and Jiří DAMBORSKÝ (203 Czech Republic, guarantor)

Edition

Applied and Environmental Microbiology, USA, 2005, 0099-2240

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

Impact factor

Impact factor: 3.818

RIV identification code

RIV/00216224:14330/05:00013656

Organization unit

Faculty of Informatics

UT WoS

000228338000068

Keywords in English

b-hexachlorocyclohexane; degradation; haloalkane dehalogenase LinB; HCH; UT26

Tags

Změněno: 19/3/2010 12:32, prof. Mgr. Jiří Damborský, Dr.

Abstract

ORIG CZ

V originále

-Hexachlorocyclohexane (b-HCH) is the most recalcitrant among the a-, b-, g-, and d-isomers of HCH, and causes serious environmental pollution problems. We demonstrate here that the haloalkane dehalogenase LinB, reported earlier to mediate the second step in the degradation of g-HCH in Sphingomonas paucimobilis UT26, metabolizes b-HCH to produce 2,3,4,5,6-pentachlorocyclohexanol.

In Czech

B-Hexachlorocyclohexane (b-HCH)způsobuje vážné environmentalní problémy.V tomto článku ukazujeme, že enzym haloalkáne dehalogenáza LinB se podílí na 2. reakčním kroku při degradaci g-HCH v bakterii Sphingomonas paucimobilis UT26, metabolizuje b-HCH a vzniká 2,3,4,5,6-pentachlorocyclohexanol.

Links

LN00A016, research and development project
Name: BIOMOLEKULÁRNÍ CENTRUM
Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular Center
ME 551, research and development project
Name: Konstrukce dehalogenujících enzymů pro biotechnologické aplikace