Nukleotidové polymorfismy u blízce příbuzných treponem a jejich detekce

MATĚJKOVÁ, Petra and David ŠMAJS. Nukleotidové polymorfismy u blízce příbuzných treponem a jejich detekce (Nucleotide polytmorphisms in genomes of closely related treponemes and their detection). In Sborník abstraktů XIII. konference mladých mikrobiologů Tomáškovy dny 2004. 2004th ed. Brno: Lékařská fakulta MU, 2004, p. 17 - 18, 1 pp.

Basic information

• Original name: Nukleotidové polymorfismy u blízce příbuzných treponem a jejich detekce
• Name in Czech: Nukleotidové polymorfismy u blízce příbuzných treponem a jejich detekce
• Name (in English): Nucleotide polytmorphisms in genomes of closely related treponemes and their detection
• Authors: MATĚJKOVÁ, Petra (203 Czech Republic) and David ŠMAJS (203 Czech Republic, guarantor).
• Edition: 2004. vyd. Brno, Sborník abstraktů XIII. konference mladých mikrobiologů Tomáškovy dny 2004, p. 17 - 18, 1 pp. 2004.
• Publisher: Lékařská fakulta MU

Other information

• Original language: Czech
• Type of outcome: Proceedings paper
• Field of Study: Genetics and molecular biology
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14110/04:00012106
• Organization unit: Faculty of Medicine
• Keywords in English: T. pallidum; DNA microarray technology
• Tags: DNA microarray technology, T. pallidum

Abstract

When comparing genomes of T. pallidum subspecies, no extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts). Anotace anglicky: No extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts).

Abstract (in English)

When comparing genomes of T. pallidum subspecies, no extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts). Anotace anglicky: No extensive differences in genome structure between pallidum and pertenue subspecies including deletions and multiplications of genes using DNA microarray technology have been found. Sequencing showed no deletions and insertions of nucleotides (no ORF shifts). One can predict, that pallidum and pertenue genomes differ in one nucleotide per every 1640 bps (altogether in 700 nts).

Links

• GA310/04/0021, research and development project: Name: Postgenomické studie syfilitické spirochety Treponema pallidum

Investor: Czech Science Foundation, Postgenomic studies on Treponema pallidum, the syphilis spirochete

• NI7351, research and development project: Name: Komparativní genomika patogenních spirochet rodu Treponema: cesta k sekvenčně specifické diagnostice

Investor: Ministry of Health of the CR