Detailed Information on Publication Record
2005
Association of the Cluster of Genetic Risk Factors in Loci Related to Glycoxidation with Diabetic Nephropathy in Type 2 Diabetes Mellitus
KAŇKOVÁ, Kateřina, Andrea STEJSKALOVÁ, Lukáš PÁCAL, Miluše HERTLOVÁ, Darja KRUSOVÁ et. al.Basic information
Original name
Association of the Cluster of Genetic Risk Factors in Loci Related to Glycoxidation with Diabetic Nephropathy in Type 2 Diabetes Mellitus
Name in Czech
Asociace souboru genetických rizikových factorů v lokusech ve vztahu k glykoxidaci s diabetickou nefropatií u diabetu typu 2
Authors
KAŇKOVÁ, Kateřina (203 Czech Republic, guarantor), Andrea STEJSKALOVÁ (203 Czech Republic), Lukáš PÁCAL (203 Czech Republic), Miluše HERTLOVÁ (203 Czech Republic) and Darja KRUSOVÁ (203 Czech Republic)
Edition
2005
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30202 Endocrinology and metabolism
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/05:00012505
Organization unit
Faculty of Medicine
Keywords in English
glycoxidation; AGEs; diabetes; nephropathy; susceptibility
Tags
Změněno: 2/4/2010 15:17, prof. MUDr. Kateřina Kaňková, Ph.D.
V originále
We found significant association of selected genetic variants in the RAGE, SOD2 and PARP-1 genes with the presence of DN in type 2 diabetics and, in the case of RAGE and PARP-1, also with acceleration of DN onset. We therefore conclude that those htSNPs could be regarded disease markers of DN.
In Czech
Nalezli jsme vyznamnou asociaci vybranych genetickych variant v RAGE, SOD2 a PARP-1 genech s DN u diabetu typu 2 a v pripade RAGE a PARP-1, take s akceleraci nastupu DN.
Links
| GP303/02/D127, research and development project |
| ||
| MSM 141100002, plan (intention) |
|