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@proceedings{572748, author = {Závodná, Eva and Hrstková, Hana and Nováková, Zuzana and Fišer, Bohumil and Honzíková, Nataša}, booktitle = {14th Meeting of Paediatric Research of Cenral European Countries}, keywords = {baroreflex sensitivity; developemnt; children; adolescents}, language = {cze}, title = {Age related changes of baroreflex sensitivity in children and adolescents}, year = {2005} }
TY - CONF ID - 572748 AU - Závodná, Eva - Hrstková, Hana - Nováková, Zuzana - Fišer, Bohumil - Honzíková, Nataša PY - 2005 TI - Age related changes of baroreflex sensitivity in children and adolescents KW - baroreflex sensitivity KW - developemnt KW - children KW - adolescents N2 - The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity with age. ER -
ZÁVODNÁ, Eva, Hana HRSTKOVÁ, Zuzana NOVÁKOVÁ, Bohumil FIŠER and Nataša HONZÍKOVÁ. Age related changes of baroreflex sensitivity in children and adolescents. In \textit{14th Meeting of Paediatric Research of Cenral European Countries}. 2005.
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