Detailed Information on Publication Record
2005
Age related changes of baroreflex sensitivity in children and adolescents
ZÁVODNÁ, Eva, Hana HRSTKOVÁ, Zuzana NOVÁKOVÁ, Bohumil FIŠER, Nataša HONZÍKOVÁ et. al.Basic information
Original name
Age related changes of baroreflex sensitivity in children and adolescents
Name in Czech
Na věku závislé změny baroreflexní citlivosti u dětí a dospívajících
Name (in English)
Age related changes of baroreflex sensitivity in children and adolescents
Authors
ZÁVODNÁ, Eva (203 Czech Republic, guarantor), Hana HRSTKOVÁ (203 Czech Republic), Zuzana NOVÁKOVÁ (203 Czech Republic), Bohumil FIŠER (203 Czech Republic) and Nataša HONZÍKOVÁ (203 Czech Republic)
Edition
14th Meeting of Paediatric Research of Cenral European Countries, 2005
Other information
Language
Czech
Type of outcome
Konferenční abstrakt
Field of Study
30105 Physiology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/05:00013798
Organization unit
Faculty of Medicine
Keywords in English
baroreflex sensitivity; developemnt; children; adolescents
Změněno: 1/4/2010 17:24, MUDr. Bc. Eva Závodná, Ph.D.
V originále
The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity with age.
In English
The aim of the study was to investigate the development of noninvasively determined baroreflex sensitivity in age between 11 to 18 years. Continuous 5 min blood pressure readings were recorded in 332 healthy subjects. Beat-to-beat values of inter beat intervals (IBI), systolic blood pressures (SBP) were measured. Baroreflex sensitivity in ms/mmHg (BRS) and in mHz/mmHg (BRSf) was determined by spectral analysis. BRS did not correlate with age, BRSf significantly decrease with age (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Multiregression analysis showed significant decrease of BRS with age after standardization to IBI. The limits of BRS were estimated for the whole group: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.9. BRS was unchanged in particular age groups, but it was dependent on IBI. Standardization of BRS on IBI disclosed its decrease with age. BRSf is IBI-independent and better reflects the development of baroreflex sensitivity with age.
Links
| MSM0021622402, plan (intention) |
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| NR8006, research and development project |
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