Other formats:
BibTeX
LaTeX
RIS
@inproceedings{586787,
author = {Šimek, Zdeněk and Bečanová, Jitka and Šimek, Zdeněk},
address = {Ovidius University of Constanta, Romania},
booktitle = {Book of Abstracts-3rd Bleach Sea Basin Conference on Analytical Chemistry. Process Related Environmental Analytical Chemistry},
keywords = {nitroaromatic explosives; liquid chromatography; capillary electrophoresis},
language = {eng},
location = {Ovidius University of Constanta, Romania},
isbn = {614-291-4},
pages = {183-183},
publisher = {Ovidius University Press},
title = {Detremination of nitroaromatic explosives and product of their biotransformation by liquid chromatography and capillary electrophoresis},
year = {2005}
}
TY - JOUR
ID - 586787
AU - Šimek, Zdeněk - Bečanová, Jitka - Šimek, Zdeněk
PY - 2005
TI - Detremination of nitroaromatic explosives and product of their biotransformation by liquid chromatography and capillary electrophoresis
PB - Ovidius University Press
CY - Ovidius University of Constanta, Romania
SN - 6142914
KW - nitroaromatic explosives
KW - liquid chromatography
KW - capillary electrophoresis
N2 - The most used explosives contain nitroderivatives of toluene such as 2,4,6-trinitrotoluene (TNT). TNT, other trinitrotoluenes and products of their biotranformations, aminodinitrotoluenes (ADNT) and diaminonitrotoluenes (DANT) are widely distributed in the environment as a consequence of extensive usage in military zones and as a result of wrong handling. The various nitroaromatic compounds have been found as contaminants in soils at munitions manufacturing facilities, storage depots, and sites of the explosives use. TNT is often stepwise biologically reduced to aminodinitrotoluenes and diaminonitrotoluenes in the environment. They have mutagenic, carcinogenic and toxic effects. TNT, 2-ADNT, 4-ADNT, 2,4-DANT, 2,6-DANT have been found to be cytotoxic presumably due to induced oxidative stress. TNT, and the TNT-derived metabolites demonstrate mutagenic capability. According to EPA, TNT is possible human carcinogen. The most commonly used method for the analysis of nitrotoluenes and aminonitrotoluenes is high performance liquid chromatography (HPLC) with UV detection due to its widespread availability. At present, electromigration methods are used due to their unrivalled separation efficiency. Comparison of retention behaviour of selected nitroderivatives of toluene and aminonitroderivatives of toluene in high performance liquid chromatography (HPLC), with their electromigration behaviour in capillary electrochromatography (CEC) and micellar electrokinetic chromatography (MECC) separation systems is presented. Analytical column with octadecyl stationary phase was used for HPLC separation, fused silica capillary filled with octadecylsilica stationary phase was used for CEC experiments and the standard bare fused silica capillary for MECC. Effect of pH and concentration of background electrolyte, sodium dodecylsulphate (SDS) concentration and organic modifier content was investigated in electrophoretic methods. Effect of mobile phase composition and different gradient elutions was studied in reversed phase liquid chromatography system. The applicability of separation method under investigation for determination of nitroderivatives of toluene in environmental samples is discussed.
ER -
ŠIMEK, Zdeněk and Jitka BEČANOVÁ. Detremination of nitroaromatic explosives and product of their biotransformation by liquid chromatography and capillary electrophoresis. In ŠIMEK, Zdeněk. \textit{Book of Abstracts-3rd Bleach Sea Basin Conference on Analytical Chemistry. Process Related Environmental Analytical Chemistry}. Ovidius University of Constanta, Romania: Ovidius University Press, 2005, p.~183-183. ISBN~614-291-4.
|
