| BRETON, Christelle, Lenka ŠNAJDROVÁ, Charlotte JEANNEAU, Jaroslav KOČA and Anne IMBERTY. Structures and mechanisms of glycosyltransferases. Glycobiology. Oxford: Oxford University Press, 2006, vol. 16, No 2, p. 29R-37R, 9 pp. ISSN 0959-6658. |
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@article{588142,
author = {Breton, Christelle and Šnajdrová, Lenka and Jeanneau, Charlotte and Koča, Jaroslav and Imberty, Anne},
article_location = {Oxford},
article_number = {2},
keywords = {glycosyltransferases; mechanism of reaction; structural characteristics; on-line database},
language = {eng},
issn = {0959-6658},
journal = {Glycobiology},
title = {Structures and mechanisms of glycosyltransferases},
url = {http://www.cermav.cnrs.fr/cgi-bin/rxgt/rxgt.cgi},
volume = {16},
year = {2006}
}
TY - JOUR
ID - 588142
AU - Breton, Christelle - Šnajdrová, Lenka - Jeanneau, Charlotte - Koča, Jaroslav - Imberty, Anne
PY - 2006
TI - Structures and mechanisms of glycosyltransferases
JF - Glycobiology
VL - 16
IS - 2
SP - 29R-37R
EP - 29R-37R
PB - Oxford University Press
SN - 09596658
KW - glycosyltransferases
KW - mechanism of reaction
KW - structural characteristics
KW - on-line database
UR - http://www.cermav.cnrs.fr/cgi-bin/rxgt/rxgt.cgi
N2 - Glycosyltransferases catalyze the transfer of a sugar moiety from an activated donor sugar onto saccharide and non-saccharide acceptors. A sequence-based classification spreads glycosyltransferases in a large number of families thus reflecting the variety of molecules that can be used as acceptors. In contrast, this enzyme family is characterized by a more conserved 3D architecture. Until recently, only two different folds (GT-A and GT-B) have been identified for solved crystal structures. The recent report of a structure for a bacterial sialyltransferase allows the defination of a new fold family. Progress in the elucidation of the structures and mechanisms of glycosyltransferases are discussed in this review. To accomodate the growing number of crystal structures, the 3D-glycosyltransferase database has been created to gather structural information concerning this class of enzymes.
ER -
BRETON, Christelle, Lenka ŠNAJDROVÁ, Charlotte JEANNEAU, Jaroslav KOČA and Anne IMBERTY. Structures and mechanisms of glycosyltransferases. \textit{Glycobiology}. Oxford: Oxford University Press, 2006, vol.~16, No~2, p.~29R-37R, 9 pp. ISSN~0959-6658.
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