Extracellular diffusion parameters during and after unilateral carotid occlusion in rat

ŠLAIS, Karel, Aleš HOMOLA and Eva SYKOVÁ. Extracellular diffusion parameters during and after unilateral carotid occlusion in rat. In Sborník abstrakt 5. konference České neurovědecké společnosti. Praha: Czech Neuroscience Society, 2005, p. 81-81.

Basic information

Original name

Extracellular diffusion parameters during and after unilateral carotid occlusion in rat

Name in Czech

Extracelulární difúzní parametry v průběhu a po jednostranné okluzi karotid u potkanů

Authors

ŠLAIS, Karel (203 Czech Republic, guarantor), Aleš HOMOLA (203 Czech Republic) and Eva SYKOVÁ (203 Czech Republic)

Edition

Praha, Sborník abstrakt 5. konference České neurovědecké společnosti, p. 81-81, 1 pp. 2005

Publisher

Czech Neuroscience Society

---

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/05:00014234

Organization unit

Faculty of Medicine

Keywords in English

diffusion; ischemia; carotid occlusion; stroke

Tags

carotid occlusion, Diffusion, ischemia, Stroke

Tags

International impact

---

Abstract

V originále

Measurements of the ECS diffusion parameters in the brain have shown that a decreases and l increases during global cerebral ischemia, but there is a lack of information about the ECS parameters during hypoxia-ischemia and in the post-ischemic period after unilateral carotid occlusion. The observed post-ischemic increase in a and decrease in l suggest that extrasynaptic communication between neurons and glia is altered during the post-ischemic period. Moreover, the concentrations of neuroactive substances, metabolites and applied drugs may be altered and could play an important role in the recovery process from stroke.

In Czech

Práce studovala změny difúzních parametrů mozku v průběhu a po jednostranné okluzi karotid se současnou hypoxiií u potkanů. Byly prokázány změny extracelulárního prostoru a tortuozity jak v průběhu, tak v postischemické fázi experimentu.

---

Links

MSM0021622404, plan (intention)

Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.