Environmental xenobiotics and nuclear receptors-Interactions, effects and in vitro assessment

JANOŠEK, Jaroslav, Klára HILSCHEROVÁ, Luděk BLÁHA and Ivan HOLOUBEK. Environmental xenobiotics and nuclear receptors-Interactions, effects and in vitro assessment. Toxicology in vitro. 2005, vol. 20, No 1, p. 18-37. ISSN 0887-2333.

Basic information

• Original name: Environmental xenobiotics and nuclear receptors-Interactions, effects and in vitro assessment
• Name in Czech: Environmentální xenobiotika a nukleární receptory
• Authors: JANOŠEK, Jaroslav (203 Czech Republic), Klára HILSCHEROVÁ (203 Czech Republic), Luděk BLÁHA (203 Czech Republic, guarantor) and Ivan HOLOUBEK (203 Czech Republic).
• Edition: Toxicology in vitro, 2005, 0887-2333.

Other information

• Original language: English
• Type of outcome: Article in a journal
• Field of Study: 30304 Public and environmental health
• Country of publisher: Netherlands
• Confidentiality degree: is not subject to a state or trade secret
• Impact factor: Impact factor: 1.754
• RIV identification code: RIV/00216224:14310/05:00012845
• Organization unit: Faculty of Science
• UT WoS: 000235129700002
• Keywords in English: Environmental xenobiotics and nuclear receptors
• Tags: International impact, Reviewed

Abstract

This throughout literatur review summarizes actual existing information on the interactions of environmental xenobiotics with nuclear receptors. It includes characterization of the receptors and their involvement in the mechanisms of action, interactions with xenobiotics and in vitro assessment.

Abstract (in Czech)

Ttoto detailní review shrnuje aktuální stav znalostí v oblasti interakce environmentálních xenobiotik s jadernými receptory. Zahrnuje charakterizaci vybraných významných receptorů, jejich úlohu v mechanismu účinku, interakce s xenobiotiky a hodnocení těchto interakcí in vitro.

Links

• GA525/03/0367, research and development project: Name: Ekotoxikologie persistentních organických polutantů životního prostředí

Investor: Czech Science Foundation, Ecotoxicology of persistent organic environmental pollutants

• GP525/05/P160, research and development project: Name: In vitro modely pro studium endokrinní disrupce - účinky tradičních a nových typů persistentních organických polutantů

Investor: Czech Science Foundation, In vitro models for study of endocrine disruption - effects of traditional and new types of persistent organic pollutants

• MSM0021622412, plan (intention): Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)