J 2005

Comparison between respondres and nonresponders in first-episode schizophrenia

ČEŠKOVÁ, Eva, Radovan PŘIKRYL, Tomáš KAŠPÁREK and Hana KUČEROVÁ

Basic information

Original name

Comparison between respondres and nonresponders in first-episode schizophrenia

Name in Czech

Srovnání mezi respondéry a nonrespondéry první epizody schizofrenie

Name (in English)

Comparison between responders and nonresponders in first-episode schizophrenia

Authors

ČEŠKOVÁ, Eva (203 Czech Republic, guarantor), Radovan PŘIKRYL (203 Czech Republic), Tomáš KAŠPÁREK (203 Czech Republic) and Hana KUČEROVÁ (203 Czech Republic)

Edition

European Neuropsychopharmacology, Amsterdam, The Netherlands, Elservier Science B.V. 2005, 0924-977X

Other information

Language

Czech

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.510

RIV identification code

RIV/00216224:14110/05:00014281

Organization unit

Faculty of Medicine

UT WoS

000233860601009

Keywords in English

first-episode schizophrenia; responders; nonresponders
Změněno: 19/6/2009 14:46, prof. MUDr. Eva Češková, CSc.

Abstract

V originále

1)to asses in details the psychopatology before and after the acute antipsychotic treatment, 2)to compare responders and nonresponders. Method used: Male patients consecutively (November 1997 to March 2004) hospitalised with first-episode schizophrenia (according to ICD 10) were included. Clinical assessment was performed using the Positive and Negative Syndrome Scale (PANSS) after admission (before treatment)and at discharge. The response rate (defined as minimally 30% reduction from baseline in the PANSS total score) was evaluated at discharge. After a baseline assessment all patients were treated openly by monotherapy with an antipsychotics, the doses were individualised. The statistical analysis was made by means of the t-test (the Wilcoxon matched-pairs test and testing for differences between means)

In English

1)to asses in details the psychopatology before and after the acute antipsychotic treatment, 2)to compare responders and nonresponders. Method used: Male patients consecutively (November 1997 to March 2004) hospitalised with first-episode schizophrenia (according to ICD 10) were included. Clinical assessment was performed using the Positive and Negative Syndrome Scale (PANSS) after admission (before treatment)and at discharge. The response rate (defined as minimally 30% reduction from baseline in the PANSS total score) was evaluated at discharge. After a baseline assessment all patients were treated openly by monotherapy with an antipsychotics, the doses were individualised. The statistical analysis was made by means of the t-test (the Wilcoxon matched-pairs test and testing for differences between means)

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.