The development of baroreflex sensitivity at the age between 11 and 21 years
ZÁVODNÁ, Eva, Nataša HONZÍKOVÁ, Zuzana NOVÁKOVÁ, Miroslav JÍRA and Bohumil FIŠER. The development of baroreflex sensitivity at the age between 11 and 21 years. 2005. |
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Basic information | |
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Original name | The development of baroreflex sensitivity at the age between 11 and 21 years |
Name in Czech | Vývoj citlivosti baroreflexu ve věku 11 - 21 let |
Authors | ZÁVODNÁ, Eva (203 Czech Republic, guarantor), Nataša HONZÍKOVÁ (203 Czech Republic), Zuzana NOVÁKOVÁ (203 Czech Republic), Miroslav JÍRA (203 Czech Republic) and Bohumil FIŠER (203 Czech Republic). |
Edition | 2005. |
Other information | |
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Original language | English |
Type of outcome | Conference abstract |
Field of Study | 30105 Physiology |
Country of publisher | Italy |
Confidentiality degree | is not subject to a state or trade secret |
RIV identification code | RIV/00216224:14110/05:00014303 |
Organization unit | Faculty of Medicine |
UT WoS | 000230639802032 |
Keywords (in Czech) | vývoj; děti; adolescenti; citlivost baroreflexu |
Keywords in English | development; children; adolescent; baroreflex sensitivity |
Tags | adolescent, baroreflex sensitivity, children, development |
Tags | International impact, Reviewed |
Changed by | Changed by: MUDr. Bc. Eva Závodná, Ph.D., učo 19752. Changed: 1/4/2010 17:52. |
Abstract |
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The aim of the study was to evaluate the development of baroreflex sensitivity and to determine its physiological limits in young population. We found that BRS (ms/mmHg) was age-independent in particular age subgroups, but it correlated with the mean inter-beat intervals (IBI). However multiple regression analysis showed that BRS was also age-dependent, but this relationship was overlaid by the IBI prolongation with age. On the other hand, baroreflex sensitivity (BRSf) expressed in mHz/mmHg decline with age and seemed to be more sensitive on baroreflex sensitivity development in case of changes of the mean IBI. The limits of BRS showed that the value of 5th percentile of healthy young subjects was under the value of BRS linked with hypertension in adults. |
Abstract (in Czech) |
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Cílem této studie bylo určit vývoj baroreflexní citlivosti a stanovení jejích fyziologických limitů u mladé populace. Zjistili jsme, že BRS (ms/mmHg) bylo na věku nezávislé celé skupině i v jednotlivých věkových podskupinách, ale významně korelovala s průměrnými hodnotami srdečních intervalů (SI). Nicméně multiregresní analýza ukázala, že BRS je na věku závislé, ale tento vztah je překryt prodlužováním SI s věkem. Na druhé straně baroreflexní citlivost (BRSf) vyjádřená v Hz/mmHg klesá s věkem a zdá se být citlivějším parametrem baroreflexní citlivosti v případě změn SI. Limity BRS ukázaly, že hodnota 5. percentilu mladých zdravých osob je pod hodnotou BRS, která je spojována s hypertenzí u dospělých osob. |
Links | |
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MSM0021622402, plan (intention) | Name: Časná diagnostika a léčba kardiovaskulárních chorob |
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases |
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