Detailed Information on Publication Record
2005
Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.
LÁBROVÁ, Růžena, Nataša HONZÍKOVÁ, Eva MADĚROVÁ, Petra VYSOČANOVÁ, Zuzana NOVÁKOVÁ et. al.Basic information
Original name
Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.
Name in Czech
Věková závislost tloušťky intimy-medie, citlivosti baroreflexu a tepového intervalu u normotezních a hypertenzních osob.
Name (in English)
Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.
Authors
LÁBROVÁ, Růžena (203 Czech Republic, guarantor), Nataša HONZÍKOVÁ (203 Czech Republic), Eva MADĚROVÁ (203 Czech Republic), Petra VYSOČANOVÁ (203 Czech Republic), Zuzana NOVÁKOVÁ (203 Czech Republic), Eva ZÁVODNÁ (203 Czech Republic), Bohumil FIŠER (203 Czech Republic) and Bořivoj SEMRÁD (203 Czech Republic)
Edition
Physiological Research, Praha, Academy of Sciences of the Czech Rep. 2005, 0862-8408
Other information
Language
Czech
Type of outcome
Článek v odborném periodiku
Field of Study
30105 Physiology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 1.806
RIV identification code
RIV/00216224:14110/05:00014308
Organization unit
Faculty of Medicine
UT WoS
000234481000004
Keywords in English
Intima-media thickness; baroreflex sensitivity; hypertension; age; heart rate
Změněno: 18/6/2009 12:33, MUDr. Zuzana Nováková, Ph.D.
V originále
The interrelationship between baroreflex sensitivity expressed in ms/mmHg (BRS) or in Hz/mmHg (BRSf), carotid wall thickness (IMT), and age was investigated in 25 treated hypertensives and 23 normotensives with respect to the mean inter-beat interval (IBI) and blood pressure (BP). IMT was measured by ultrasonography. BRS and BRSf were determined by the spectral method (five-minute non-invasive beat-to-beat recording of BP and IBI, Finapres). Hypertensive patients have significantly increased IMT and decreased BRS and BRSf. The positive correlation between age and IMT and the negative correlation between age and BRS and BRSf are in agreement with the hypothesis that the age-dependent decrease of baroreflex sensitivity corresponds to the age-related structural changes of the carotid wall. Using two indices of baroreflex sensitivity, BRS and BRSf, we could show that baroreflex sensitivity in hypertensives is lower not only due to thickening of the carotid wall, but also due to aging.
In English
The interrelationship between baroreflex sensitivity expressed in ms/mmHg (BRS) or in Hz/mmHg (BRSf), carotid wall thickness (IMT), and age was investigated in 25 treated hypertensives and 23 normotensives with respect to the mean inter-beat interval (IBI) and blood pressure (BP). IMT was measured by ultrasonography. BRS and BRSf were determined by the spectral method (five-minute non-invasive beat-to-beat recording of BP and IBI, Finapres). Hypertensive patients have significantly increased IMT and decreased BRS and BRSf. The positive correlation between age and IMT and the negative correlation between age and BRS and BRSf are in agreement with the hypothesis that the age-dependent decrease of baroreflex sensitivity corresponds to the age-related structural changes of the carotid wall. Using two indices of baroreflex sensitivity, BRS and BRSf, we could show that baroreflex sensitivity in hypertensives is lower not only due to thickening of the carotid wall, but also due to aging.
Links
| MSM0021622402, plan (intention) |
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| NA7362, research and development project |
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