| LÁBROVÁ, Růžena, Nataša HONZÍKOVÁ, Eva MADĚROVÁ, Petra VYSOČANOVÁ, Zuzana NOVÁKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER and Bořivoj SEMRÁD. Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects. Physiological Research. Praha: Academy of Sciences of the Czech Rep., 2005, vol. 54, No 6, p. 593-600. ISSN 0862-8408. |
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@article{596451,
author = {Lábrová, Růžena and Honzíková, Nataša and Maděrová, Eva and Vysočanová, Petra and Nováková, Zuzana and Závodná, Eva and Fišer, Bohumil and Semrád, Bořivoj},
article_location = {Praha},
article_number = {6},
keywords = {Intima-media thickness; baroreflex sensitivity; hypertension; age; heart rate},
language = {cze},
issn = {0862-8408},
journal = {Physiological Research},
title = {Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.},
volume = {54},
year = {2005}
}
TY - JOUR
ID - 596451
AU - Lábrová, Růžena - Honzíková, Nataša - Maděrová, Eva - Vysočanová, Petra - Nováková, Zuzana - Závodná, Eva - Fišer, Bohumil - Semrád, Bořivoj
PY - 2005
TI - Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects.
JF - Physiological Research
VL - 54
IS - 6
SP - 593-600
EP - 593-600
PB - Academy of Sciences of the Czech Rep.
SN - 08628408
KW - Intima-media thickness
KW - baroreflex sensitivity
KW - hypertension
KW - age
KW - heart rate
N2 - The interrelationship between baroreflex sensitivity expressed in ms/mmHg (BRS) or in Hz/mmHg (BRSf), carotid wall thickness (IMT), and age was investigated in 25 treated hypertensives and 23 normotensives with respect to the mean inter-beat interval (IBI) and blood pressure (BP). IMT was measured by ultrasonography. BRS and BRSf were determined by the spectral method (five-minute non-invasive beat-to-beat recording of BP and IBI, Finapres). Hypertensive patients have significantly increased IMT and decreased BRS and BRSf. The positive correlation between age and IMT and the negative correlation between age and BRS and BRSf are in agreement with the hypothesis that the age-dependent decrease of baroreflex sensitivity corresponds to the age-related structural changes of the carotid wall. Using two indices of baroreflex sensitivity, BRS and BRSf, we could show that baroreflex sensitivity in hypertensives is lower not only due to thickening of the carotid wall, but also due to aging.
ER -
LÁBROVÁ, Růžena, Nataša HONZÍKOVÁ, Eva MADĚROVÁ, Petra VYSOČANOVÁ, Zuzana NOVÁKOVÁ, Eva ZÁVODNÁ, Bohumil FIŠER and Bořivoj SEMRÁD. Age-dependent relationship between the carotid intima-media thickness, baroreflex sensitivity, and the inter-beat interval in normotensive and hypertensive subjects. \textit{Physiological Research}. Praha: Academy of Sciences of the Czech Rep., 2005, vol.~54, No~6, p.~593-600. ISSN~0862-8408.
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