Using of electrochemical methods for studying of
metallothionein content in the human blood serum of a patient
poisoned by lead and treated by platinum.

J 2005

Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum.

PETRLOVÁ, Jitka; Ondřej BLAŠTÍK; Richard PRŮŠA; Martin KUKAČKA; David POTĚŠIL et. al.

Basic information

Original name

Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum.

Name in Czech

Použití elektrochemických metod pro studium obsahu metallothioneinu v lidském krevním séru u pacientů otrávených olovem a platinou

Authors

PETRLOVÁ, Jitka (203 Czech Republic); Ondřej BLAŠTÍK (203 Czech Republic); Richard PRŮŠA (203 Czech Republic); Martin KUKAČKA (203 Czech Republic); David POTĚŠIL (203 Czech Republic); Radka MIKELOVÁ (203 Czech Republic, guarantor); Vojtěch ADAM (203 Czech Republic); Josef ZEHNÁLEK (203 Czech Republic) and René KIZEK (203 Czech Republic)

Edition

Biomedical Papers, 2005, 1213-8118

Other information

Language

English

Type of outcome

Article in a journal

Field of Study

10405 Electrochemistry

Country of publisher

Czech Republic

Confidentiality degree

is not subject to a state or trade secret

RIV identification code

RIV/00216224:14310/05:00013144

Organization unit

Faculty of Science

Keywords in English

Metallothionein; Brdicka reaction; Peak H; Catalytic hydrogen reaction; Cancer; Lead; Differential pulse voltammetry; Adsorptive stripping voltammetry

Abstract

ORIG CZ

V originále

Metallothioneins belong to the group of intracellular, high molecular and cysteine-rich proteins whose content increase with increasing concentration of a heavy metal. Here we applied the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothionein in human blood serum of patient poisoned by lead and/or treated by platinum. The increased metallothionein concentrations in both cases were observed.

In Czech

Metalothionein patří do skupiny intracelulárních, vysokomolekulárních a na cystein bohatých proteinů

Links

GP525/04/P132, research and development project

Name: Studium obranných mechanismů rostlin při stresu způsobeném těžkými kovy

MSM0021622412, plan (intention)

Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)

Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)

Cite

PETRLOVÁ, Jitka; Ondřej BLAŠTÍK; Richard PRŮŠA; Martin KUKAČKA; David POTĚŠIL; Radka MIKELOVÁ; Vojtěch ADAM; Josef ZEHNÁLEK and René KIZEK. Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum. Biomedical Papers. 2005, vol. 149, No 2, p. 485-488. ISSN 1213-8118.

@article{618852,
   author = {Petrlová, Jitka and Blaštík, Ondřej and Průša, Richard and Kukačka, Martin and Potěšil, David and Mikelová, Radka and Adam, Vojtěch and Zehnálek, Josef and Kizek, René},
   article_number = {2},
   keywords = {Metallothionein; Brdicka reaction; Peak H; Catalytic hydrogen reaction; Cancer; Lead; Differential pulse voltammetry; Adsorptive stripping voltammetry},
   language = {eng},
   issn = {1213-8118},
   journal = {Biomedical Papers},
   title = {Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum.},
   volume = {149},
   year = {2005}
}

TY  - JOUR
ID  - 618852
AU  - Petrlová, Jitka - Blaštík, Ondřej - Průša, Richard - Kukačka, Martin - Potěšil, David - Mikelová, Radka - Adam, Vojtěch - Zehnálek, Josef - Kizek, René
PY  - 2005
TI  - Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum.
JF  - Biomedical Papers
VL  - 149
IS  - 2
SP  - 485-488
EP  - 485-488
SN  - 12138118
KW  - Metallothionein
KW  - Brdicka reaction
KW  - Peak H
KW  - Catalytic hydrogen reaction
KW  - Cancer
KW  - Lead
KW  - Differential pulse voltammetry
KW  - Adsorptive stripping voltammetry
N2  - Metallothioneins belong to the group of intracellular, high molecular and cysteine-rich proteins whose content increase with increasing concentration of a heavy metal. Here we applied the adsorptive transfer stripping differential pulse voltammetry Brdicka reaction for the determination of metallothionein in human blood serum of patient poisoned by lead and/or treated by platinum. The increased metallothionein concentrations in both cases were observed.
ER  -

PETRLOVÁ, Jitka; Ondřej BLAŠTÍK; Richard PRŮŠA; Martin KUKAČKA; David POTĚŠIL; Radka MIKELOVÁ; Vojtěch ADAM; Josef ZEHNÁLEK and René KIZEK. Using of electrochemical methods for studying of metallothionein content in the human blood serum of a patient poisoned by lead and treated by platinum. \textit{Biomedical Papers}. 2005, vol.~149, No~2, p.~485-488. ISSN~1213-8118.

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