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@inproceedings{621624,
author = {Šmajs, David and Strouhal, Michal and Matějková, Petra and Norris, S.J. and Weinstock, G.M.},
address = {United Kingdom},
booktitle = {Clinical Microbiology and Infection},
keywords = {Treponema pallidum ssp. pallidum; Treponema pallidum ssp. pertenue; Treponema paraluiscuniculi},
language = {eng},
location = {United Kingdom},
pages = {248-248},
publisher = {Blackwell Publishing},
title = {Comparison of the genomes of pathogenic treponemes, Treponema pallidum ssp. pallidum, ssp. pertenue and Treponema paraluiscuniculi.},
year = {2005}
}
TY - JOUR
ID - 621624
AU - Šmajs, David - Strouhal, Michal - Matějková, Petra - Norris, S.J. - Weinstock, G.M.
PY - 2005
TI - Comparison of the genomes of pathogenic treponemes, Treponema pallidum ssp. pallidum, ssp. pertenue and Treponema paraluiscuniculi.
PB - Blackwell Publishing
CY - United Kingdom
KW - Treponema pallidum ssp. pallidum
KW - Treponema pallidum ssp. pertenue
KW - Treponema paraluiscuniculi
N2 - Objectives. Genomes of closely related treponemes, Treponema pallidum ssp. pallidum (strains Nichols and SS14) and Treponema pallidum ssp. pertenue (Gauthier, Samoan D) were compared with the genome of Treponema paraluiscuniculi using genomic techniques. T. pallidum ssp. pallidum is the causative agent of a highly invasive human disease syphilis, T. pallidum ssp. pertenue is the causative agent of yaws and T. paraluiscuniculi is not pathogenic to humans. After labelling of chromosomal DNA using random hexamers and hybridization to the DNA microarray, at least 15 T. paraluiscuniculi genes showed significantly lower signals when compared to signals of T. pallidum ssp. pallidum.
ER -
ŠMAJS, David, Michal STROUHAL, Petra MATĚJKOVÁ, S.J. NORRIS and G.M. WEINSTOCK. Comparison of the genomes of pathogenic treponemes, Treponema pallidum ssp. pallidum, ssp. pertenue and Treponema paraluiscuniculi. In \textit{Clinical Microbiology and Infection}. United Kingdom: Blackwell Publishing, 2005, p.~248. ISSN~1470-9465.
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