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@inproceedings{621710,
author = {Pásek, Michal and Šimurda, Jiří and Orchard, Clive and Christé, Georges},
address = {Lyon},
booktitle = {Computers in cardiology 2005},
keywords = {cardiac cell; tubular system; quantitative modelling},
language = {eng},
location = {Lyon},
isbn = {0-7803-9337-6},
pages = {993-995},
publisher = {IEEE},
title = {Physiological role of transverse-axial tubular system in cardiac ventricular myocytes: a simulation study},
year = {2005}
}
TY - JOUR
ID - 621710
AU - Pásek, Michal - Šimurda, Jiří - Orchard, Clive - Christé, Georges
PY - 2005
TI - Physiological role of transverse-axial tubular system in cardiac ventricular myocytes: a simulation study
PB - IEEE
CY - Lyon
SN - 0780393376
KW - cardiac cell
KW - tubular system
KW - quantitative modelling
N2 - Experimental data related to the transverse - axial tubular system of guinea pig and rat ventricular myocytes were incorporated into quantitative models of their electrical activity. The results of simulations suggest that activity-dependent depletion of Ca within the tubular lumen decreases the intracellular Ca-load and intracellular Ca-transients in both species. However, considerable species differences in the magnitude of the depletion, its frequency dependence and the resulting effect on cellular activity were observed.
ER -
PÁSEK, Michal, Jiří ŠIMURDA, Clive ORCHARD and Georges CHRISTÉ. Physiological role of transverse-axial tubular system in cardiac ventricular myocytes: a simulation study. In \textit{Computers in cardiology 2005}. Lyon: IEEE, 2005, p.~993-995. ISBN~0-7803-9337-6.
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