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@article{632094,
author = {Mandelová, Lucie and Totušek, Jiří and Totušek, Jiří},
article_location = {Praha},
article_number = {č. 1},
keywords = {micronucleus test; broccoli; antimutagenicity; MNU},
language = {eng},
issn = {1212-1800},
journal = {Czech J. Food Sci.},
title = {Chemoprotective effects of broccoli juice treated with high presssure},
volume = {roč. 24},
year = {2006}
}
TY - JOUR
ID - 632094
AU - Mandelová, Lucie - Totušek, Jiří - Totušek, Jiří
PY - 2006
TI - Chemoprotective effects of broccoli juice treated with high presssure
JF - Czech J. Food Sci.
VL - roč. 24
IS - č. 1
SP - s. 19-25
EP - s. 19-25
SN - 12121800
KW - micronucleus test
KW - broccoli
KW - antimutagenicity
KW - MNU
N2 - We investigated chemoprotective effects of broccoli juice, treated by high pressure method, using 500 MPa for a period of 10 minutes. By the use of this method, the conservation of nutritionally important substances occurs (for example vitamins, polyphenolic compounds, glucosinolates and other constituent substances). We followed the inhibition of mutagenicity of the model mutagen, N-nitroso-N-methylurea (MNU) by means of in vivo micronucleus test. After fourteen-days application of broccoli juice (0.2 ml/10 g of body weight of mouse) and after single administration of MNU mutagen (50 mg/kg), a statistically significant decrease (p<0.01) occured, of number of micronuclei induced by the application of MNU. Broccoli juice treated by high pressure, therefore seems to have a preventive potential against MNU-induced micronuclei formation in BALB/C mouse bone marrow cells.
ER -
MANDELOVÁ, Lucie a Jiří TOTUŠEK. Chemoprotective effects of broccoli juice treated with high presssure. \textit{Czech J. Food Sci.}. Praha, 2006, roč. 24, č. 1, s.~s. 19-25, 7 s. ISSN~1212-1800.
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