Chemoprotective effects of broccoli juice treated with high presssure

MANDELOVÁ, Lucie and Jiří TOTUŠEK. Chemoprotective effects of broccoli juice treated with high presssure. Czech J. Food Sci. Praha, 2006, roč. 24, č. 1, p. s. 19-25, 7 pp. ISSN 1212-1800.

Basic information

Original name

Chemoprotective effects of broccoli juice treated with high presssure

Name in Czech

Chemoprotektivní účinky brokolicové šťávy ošetřené vysokým tlakem

Authors

MANDELOVÁ, Lucie (203 Czech Republic, guarantor) and Jiří TOTUŠEK (203 Czech Republic)

Edition

Czech J. Food Sci. Praha, 2006, 1212-1800

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

21101 Food and beverages

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.387

RIV identification code

RIV/00216224:14510/06:00031474

Organization unit

Faculty of Sports Studies

UT WoS

000235547300003

Keywords in English

micronucleus test; broccoli; antimutagenicity; MNU

Tags

antimutagenicity, broccoli, micronucleus test, MNU

Tags

Reviewed

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Abstract

V originále

We investigated chemoprotective effects of broccoli juice, treated by high pressure method, using 500 MPa for a period of 10 minutes. By the use of this method, the conservation of nutritionally important substances occurs (for example vitamins, polyphenolic compounds, glucosinolates and other constituent substances). We followed the inhibition of mutagenicity of the model mutagen, N-nitroso-N-methylurea (MNU) by means of in vivo micronucleus test. After fourteen-days application of broccoli juice (0.2 ml/10 g of body weight of mouse) and after single administration of MNU mutagen (50 mg/kg), a statistically significant decrease (p<0.01) occured, of number of micronuclei induced by the application of MNU. Broccoli juice treated by high pressure, therefore seems to have a preventive potential against MNU-induced micronuclei formation in BALB/C mouse bone marrow cells.

In Czech

Zjišťovali jsem chemoprotektivní účinky brokolicové šťávy ošetřené vysokým tlakem. Sledovali jsem inhibici mutagenity modelového mutagenu (MNU) za pomoci krátkodobého testu mutagenity - in vivo mikronukeus testu. Po 14denní aplikaci brokolicové šťávy a po jednorázové aplikaci mutagenu došlo ke statisticky významnému snížení počtu mikrojader vyvoalných aplikací MNU. Brokolicová šťáva ošetřená vysokým tlakem pravděpodobně snižuje mutagenitu MNU u BALB/C myších samců.