SABIN, Charles, Edward P. MITCHELL, Martina POKORNÁ, Catherine GAUTIER, J. UTILE, Michaela WIMMEROVÁ a Anne IMBERTY. Binding of different monosaccharides by lectin PA-IIL from Pseudomonas aeruginosa: Thermodynamics data correlated with X-ray structures. FEBS Letters. Amsterdam: Elsevier Science B.V., 2006, roč. 580, č. 2, s. 982-987. ISSN 0014-5793. |
Další formáty:
BibTeX
LaTeX
RIS
@article{633505, author = {Sabin, Charles and Mitchell, Edward P. and Pokorná, Martina and Gautier, Catherine and Utile, J. and Wimmerová, Michaela and Imberty, Anne}, article_location = {Amsterdam}, article_number = {2}, keywords = {Pseudomonas aeruginosa; lectin; cystic fibrosis}, language = {eng}, issn = {0014-5793}, journal = {FEBS Letters}, title = {Binding of different monosaccharides by lectin PA-IIL from Pseudomonas aeruginosa: Thermodynamics data correlated with X-ray structures}, volume = {580}, year = {2006} }
TY - JOUR ID - 633505 AU - Sabin, Charles - Mitchell, Edward P. - Pokorná, Martina - Gautier, Catherine - Utile, J. - Wimmerová, Michaela - Imberty, Anne PY - 2006 TI - Binding of different monosaccharides by lectin PA-IIL from Pseudomonas aeruginosa: Thermodynamics data correlated with X-ray structures JF - FEBS Letters VL - 580 IS - 2 SP - 982-987 EP - 982-987 PB - Elsevier Science B.V. SN - 00145793 KW - Pseudomonas aeruginosa KW - lectin KW - cystic fibrosis N2 - The PA-IIL lectin from Pseudomonas aeruginosa is involved in host recognition and biofilm formation. The lectin displays an unusually high affinity for fucose but also binds to L-fucose, L-galactose and D-arabinose that differ only by the group at position 5 of the sugar ring. ITC experiments provided precise determination of affinity for the three methyl-glycosides and revealed a large enthalpy contribution. The crystal structures of the complexes of PA-IIL with L-galactose and Met-â-D-arabinoside have been determined and compared with the PA-IIL/fucose complex described previously. Combination of structures and thermodynamics provided clues for the role of the hydrophobic group in affinity. ER -
SABIN, Charles, Edward P. MITCHELL, Martina POKORNÁ, Catherine GAUTIER, J. UTILE, Michaela WIMMEROVÁ a Anne IMBERTY. Binding of different monosaccharides by lectin PA-IIL from Pseudomonas aeruginosa: Thermodynamics data correlated with X-ray structures. \textit{FEBS Letters}. Amsterdam: Elsevier Science B.V., 2006, roč.~580, č.~2, s.~982-987. ISSN~0014-5793.
|