Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice

LANDA, Leoš, Karel ŠLAIS and Alexandra ŠULCOVÁ. Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice. Neuroendocrinology Letters. Stockholm: Society of Integrated Sciences, 2006, vol. 27, 1-2, p. 63-69. ISSN 0172-780X.

Basic information

Original name

Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice

Name in Czech

Zapojení aktivity kanabinoidních CB1 a CB2 receptorů do rozvoje behaviorální senzitizace k účinkům metamfetaminu u myší

Authors

LANDA, Leoš (203 Czech Republic, guarantor), Karel ŠLAIS (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic)

Edition

Neuroendocrinology Letters, Stockholm, Society of Integrated Sciences, 2006, 0172-780X

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Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30104 Pharmacology and pharmacy

Country of publisher

Sweden

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.924

RIV identification code

RIV/00216224:14110/06:00016879

Organization unit

Faculty of Medicine

UT WoS

000238667700008

Keywords in English

methamphetamine; cannabinoids; behavioural sensitization; locomotion; mice

Tags

behavioural sensitization, cannabinoids, locomotion, methamphetamine, mice

Tags

International impact, Reviewed

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Abstract

V originále

Methamphetamine produced significant sensitization to its stimulatory effect on locomotion. Methanandamide pre-treatment elicited cross-sensitization to methamphetamine effect, whereas pre-treatment with JWH 015 did not. Combined pre-treatment with methamphetamine+AM 251 suppressed sensitization to methamphetamine.

In Czech

Opakovaná aplikace metamfetaminu vyvolala senzitizaci k jeho stimulačním účinkům na lokomoci. Opakovaná aplikace metanandamidu vedla ke vzniku zkřížené senzitizace k účinkům metamfetaminu, zatímco opakovaná aplikace látky JWH 015 k rozvoji tohoto fenoménu nevedla. Kombinovaná opakovaná aplikace metamfetaminu + látky AM 251 senzitizaci k metamfetaminu potlačila.

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Links

MSM0021622404, plan (intention)

Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.