LANDA, Leoš, Karel ŠLAIS and Alexandra ŠULCOVÁ. Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice. Neuroendocrinology Letters. Stockholm: Society of Integrated Sciences, 2006, vol. 27, 1-2, p. 63-69. ISSN 0172-780X.
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Basic information
Original name Involvement of cannabinoid CB1 and CB2 receptor activity in the development of behavioural sensitization to methamphetamine effects in mice
Name in Czech Zapojení aktivity kanabinoidních CB1 a CB2 receptorů do rozvoje behaviorální senzitizace k účinkům metamfetaminu u myší
Authors LANDA, Leoš (203 Czech Republic, guarantor), Karel ŠLAIS (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic).
Edition Neuroendocrinology Letters, Stockholm, Society of Integrated Sciences, 2006, 0172-780X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher Sweden
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.924
RIV identification code RIV/00216224:14110/06:00016879
Organization unit Faculty of Medicine
UT WoS 000238667700008
Keywords in English methamphetamine; cannabinoids; behavioural sensitization; locomotion; mice
Tags behavioural sensitization, cannabinoids, locomotion, methamphetamine, mice
Tags International impact, Reviewed
Changed by Changed by: doc. Mgr. MVDr. Leoš Landa, Ph.D., učo 70449. Changed: 22/6/2009 09:32.
Abstract
Methamphetamine produced significant sensitization to its stimulatory effect on locomotion. Methanandamide pre-treatment elicited cross-sensitization to methamphetamine effect, whereas pre-treatment with JWH 015 did not. Combined pre-treatment with methamphetamine+AM 251 suppressed sensitization to methamphetamine.
Abstract (in Czech)
Opakovaná aplikace metamfetaminu vyvolala senzitizaci k jeho stimulačním účinkům na lokomoci. Opakovaná aplikace metanandamidu vedla ke vzniku zkřížené senzitizace k účinkům metamfetaminu, zatímco opakovaná aplikace látky JWH 015 k rozvoji tohoto fenoménu nevedla. Kombinovaná opakovaná aplikace metamfetaminu + látky AM 251 senzitizaci k metamfetaminu potlačila.
Links
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
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