Detailed Information on Publication Record
2006
Toxic effects of cyanobacterial biomass in Japanese quail
PAŠKOVÁ, Veronika, Klára HILSCHEROVÁ, Pavel BABICA, Blanka SKOČOVSKÁ, Jana HORÁKOVÁ et. al.Basic information
Original name
Toxic effects of cyanobacterial biomass in Japanese quail
Name in Czech
Studie účinku biomasy sinic na křepelku japonskou
Authors
PAŠKOVÁ, Veronika (203 Czech Republic, guarantor, belonging to the institution), Klára HILSCHEROVÁ (203 Czech Republic, belonging to the institution), Pavel BABICA (203 Czech Republic, belonging to the institution), Blanka SKOČOVSKÁ (203 Czech Republic), Jana HORÁKOVÁ (203 Czech Republic), Jií PIKULA (203 Czech Republic) and Blahoslav MARŠÁLEK (203 Czech Republic, belonging to the institution)
Edition
SETAC Europe 16th Annual Meeting, Abstract Book, 2006
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30304 Public and environmental health
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/06:00015344
Organization unit
Faculty of Science
Keywords in English
cyanobacteria; microcystin; bird; oxidative stress; detoxification; antioxidative system
Změněno: 29/4/2011 12:57, prof. RNDr. Luděk Bláha, Ph.D.
V originále
Cyanobacteria produce wide range of toxic compounds (cyanotoxins) which became important contaminants of aquatic ecosystems. Although several case studies implicated at least a contribution of toxic cyanobacterial blooms to the mass deaths of different bird species, there is a lack of toxicological experiments focused on avian toxicity of cyanobacteria or cyanotoxins. The aim of this study was to investigate the effects of cyanobacterial biomass using OECD 205: Avian dietary toxicity test with Japanese quail (Coturnix coturnix japonica). Animals were exposed to homogenized cyanobacterial bloom of Microcystis aeruginosa (containing the most prevalent cyanotoxins microcystins) in acute and (sub)chronic study. Effects on biochemical markers related to oxidative stress and detoxication were investigated in different tissues. Exposure to cyanobacterial biomass induced modulations of enzymatic and nonenzymatic antioxidants (including glutathione level and related enzymes) as well as lipid peroxidation.
In Czech
Sinice produkují široké spektrum látek, které ovlivňují vodní ekosystém. Tato studie se zabývala účinkem sinicových toxinů microcystinů na modulaci antioxidativních a detoxifikačních markerů u ptáků, konkrétně u křepelky japonské v akutní a chronické studii. Byly pozorovány významné účinky na biochemické úrovni a rovněž indukce oxidativního stresu.
Links
AV0Z60050516, plan (intention) |
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MSM0021622412, plan (intention) |
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