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@proceedings{638244, author = {Závodná, Eva and Nováková, Zuzana and Honzíková, Nataša and Fišer, Bohumil and Jíra, Miroslav and Šťastná, Jana and Hrstková, Hana}, booktitle = {15th Meeting of Paediatric Research of Central European Countries}, keywords = {anthracycline; antitumour therapy; physical activity; baroreflex sensitivity; children; adolescents;}, language = {eng}, title = {EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY}, year = {2006} }
TY - CONF ID - 638244 AU - Závodná, Eva - Nováková, Zuzana - Honzíková, Nataša - Fišer, Bohumil - Jíra, Miroslav - Šťastná, Jana - Hrstková, Hana PY - 2006 TI - EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY KW - anthracycline KW - antitumour therapy KW - physical activity KW - baroreflex sensitivity KW - children KW - adolescents; N2 - We followed effect of anthracycline therapy on physical activity, body and cardiovascular parameters in children treated for malignant tumor. We examined 21 subjects after antitumor therapy (M; 15.5b3.2 years) and 32 healthy subjects (Co; 15.7b2.1 years). In group M, 8 subjects had a non-cardiotoxic therapy (A0), and 13 children were treated with anthracyclines (A+). In group A+ vs. A0 and Co, we found significantly lower SBP. A+ compared with Co had higher BRSf; lower weight and height; lower total physical activity and physical activity related to 1 kg of body weight. In whole group M, we found negative correlation between dose of anthracyclines and SBP and total physical activity. The multiple regression in group M shown that SBP was significantly related to the duration of period without antitumor therapy and to the dosage of anthracyclines. BRSf significantly correlated with body weight, physical activity related to 1 kg of body weight, time since therapy and SBP. ER -
ZÁVODNÁ, Eva, Zuzana NOVÁKOVÁ, Nataša HONZÍKOVÁ, Bohumil FIŠER, Miroslav JÍRA, Jana ŠŤASTNÁ and Hana HRSTKOVÁ. EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY. In \textit{15th Meeting of Paediatric Research of Central European Countries}. 2006.
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