Detailed Information on Publication Record
2006
EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY
ZÁVODNÁ, Eva, Zuzana NOVÁKOVÁ, Nataša HONZÍKOVÁ, Bohumil FIŠER, Miroslav JÍRA et. al.Basic information
Original name
EFFECT OF ANTHRACYCLINE THERAPY ON CARDIOVASCULAR REGULATION AND PHYSICAL ACTIVITY
Name in Czech
Vliv léby antracykliny na kardiovaskulární regulaci a fyzickou aktivitu
Authors
ZÁVODNÁ, Eva (203 Czech Republic, guarantor), Zuzana NOVÁKOVÁ (203 Czech Republic), Nataša HONZÍKOVÁ (203 Czech Republic), Bohumil FIŠER (203 Czech Republic), Miroslav JÍRA (203 Czech Republic), Jana ŠŤASTNÁ (203 Czech Republic) and Hana HRSTKOVÁ (203 Czech Republic)
Edition
15th Meeting of Paediatric Research of Central European Countries, 2006
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30105 Physiology
Country of publisher
Austria
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/06:00016959
Organization unit
Faculty of Medicine
Keywords (in Czech)
antracykliny; protinádorová léčba; fyzická aktivita; citlivost baroreflexu; děti; adolescenti
Keywords in English
anthracycline; antitumour therapy; physical activity; baroreflex sensitivity; children; adolescents;
Tags
Tags
International impact, Reviewed
Změněno: 1/4/2010 17:08, MUDr. Bc. Eva Závodná, Ph.D.
V originále
We followed effect of anthracycline therapy on physical activity, body and cardiovascular parameters in children treated for malignant tumor. We examined 21 subjects after antitumor therapy (M; 15.5b3.2 years) and 32 healthy subjects (Co; 15.7b2.1 years). In group M, 8 subjects had a non-cardiotoxic therapy (A0), and 13 children were treated with anthracyclines (A+). In group A+ vs. A0 and Co, we found significantly lower SBP. A+ compared with Co had higher BRSf; lower weight and height; lower total physical activity and physical activity related to 1 kg of body weight. In whole group M, we found negative correlation between dose of anthracyclines and SBP and total physical activity. The multiple regression in group M shown that SBP was significantly related to the duration of period without antitumor therapy and to the dosage of anthracyclines. BRSf significantly correlated with body weight, physical activity related to 1 kg of body weight, time since therapy and SBP.
In Czech
Sledovali jsme vliv antracyklinové léčby na fyzickou aktivitu, tělesné a kardiovaskulární parametry u dětí léčených pro maligní nádor. Vyšetili jsme 21 dětí po protinádorové léčbě (M) a 32 zdravých osob (Co). Ve skupin M bylo 8 dětí léčeno nekardiotoxickou léčbou (A0) a 13 dětí bylo léčeno antracykliny (A+). V porovnání ke skupinám A0 a Co, skupina A+měla nižší systolický tlak (STK), vyšší baroreflexní senzitivitu, nižší výšku a hmotnost a fyzickou aktivitu. V celé skupin M s rostoucí dávkou antracykllinů klesal STK a fyzická aktivita.
Links
| MSM0021622402, plan (intention) |
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| NR8006, research and development project |
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