D 2006

Lipoperoxidation in elderly humans with hyperhomocysteinemia in the course of selenium supplementation

TOMANDL, Josef, Jaroslava TALLOVÁ, Michaela KRÁLÍKOVÁ and Jan KVÍČALA

Basic information

Original name

Lipoperoxidation in elderly humans with hyperhomocysteinemia in the course of selenium supplementation

Name in Czech

Lipoperoxidace u starých lidí s hyperhocysteinemií v průběhu suplementace selenem

Authors

TOMANDL, Josef (203 Czech Republic, guarantor), Jaroslava TALLOVÁ (203 Czech Republic), Michaela KRÁLÍKOVÁ (203 Czech Republic) and Jan KVÍČALA (203 Czech Republic)

Edition

Bratislava, Proceedings from XX. Biochemický zjazd, p. 363-363, 2006

Publisher

Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Russian Federation

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/06:00018869

Organization unit

Faculty of Medicine

ISBN

80-969532-6-5

Keywords in English

hyperhocysteinemi - elderly - malondialdehyde - selenium supplementation
Změněno: 20/9/2006 16:35, doc. RNDr. Josef Tomandl, Ph.D.

Abstract

ORIG CZ

V originále

Increased oxidative stress plays an important role in the aging processes. Besides, elevated plasma homocysteine, particularly evident in elderly, has been recognized as a risk factor for many pathological states including oxidative stress. Selenium as a component of antioxidative enzymes is associated with the protection against oxidative stress. The aim of this study was to assess plasma malondialdehyde as a marker of lipid peroxidation in relationship to selenium in hyperhomocysteinemic elderly subjects in the course of a long-term selenium supplementation.

In Czech

Increased oxidative stress plays an important role in the aging processes. Besides, elevated plasma homocysteine, particularly evident in elderly, has been recognized as a risk factor for many pathological states including oxidative stress. Selenium as a component of antioxidative enzymes is associated with the protection against oxidative stress. The aim of this study was to assess plasma malondialdehyde as a marker of lipid peroxidation in relationship to selenium in hyperhomocysteinemic elderly subjects in the course of a long-term selenium supplementation.

Links

NR7820, research and development project
Name: Sledování změn vybraných metabolitů v průběhu optimalizace stavu selenu v organismu
Investor: Ministry of Health of the CR