HUDEČEK, Robert, Pavel VENTRUBA, Constantinos TSOMPSOS, Eva RAČANSKÁ, Radka VAVRUŠOVÁ and Karel NOVÁK. Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques. Helen. Jour. Obstet. Gynecol. Řecko: Helen. Jour. Obstet. Gynecol, 2006, 5/2006, No 5, p. 75-79, 4 pp. ISSN 1109-4117.
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Basic information
Original name Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques
Name in Czech Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques
Name (in English) Incidence of malignancy occurance in patients treated for infertility with assisted reproduction techniques
Authors HUDEČEK, Robert, Pavel VENTRUBA, Constantinos TSOMPSOS, Eva RAČANSKÁ, Radka VAVRUŠOVÁ and Karel NOVÁK.
Edition Helen. Jour. Obstet. Gynecol, Řecko, Helen. Jour. Obstet. Gynecol, 2006, 1109-4117.
Other information
Original language řečtina stará
Type of outcome Article in a journal
Field of Study 30214 Obstetrics and gynaecology
Country of publisher Greece
Confidentiality degree is not subject to a state or trade secret
Organization unit Faculty of Medicine
Keywords in English Malignancy occurance; infertility; assisted reproduction techniques
Tags assisted reproduction techniques, infertility, Malignancy occurance
Tags International impact, Reviewed
Changed by Changed by: doc. MUDr. Robert Hudeček, Ph.D., učo 77349. Changed: 10/1/2008 12:13.
Abstract
The analysis of potential relation between assisted reproduction teqniques (ART) and enhanced risk of ovarian carcinoma (OC) was explored by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed file includes data from 12.527 assisted reproduction treatment cycles performed at 4360 patients within years 1982-2004. After the reported malignancies number assessment from the observed group clinical database (ours and NOR) further processing, statistical analysis and results comparison was followed by the Institute of Health Information and Statistics of the Czech Republic. Statistical significance of malignancy occurance was evaluated using p-value<0.01. In the file of 4360 patients was reported 41 malignancies including 6 OC this is 3.454 times 95%CI[1.625 – 6.715] over the expected incidence to this diseased group of women. NOR offered the control diseased women group by the documented 4.236% rate among the total malignant women. It must be investigated by any reservedness whether the same risk of 3.454 developing OC exists at healthy general population women submitted to infertility treatment (p-value=0.004 Yates correction).
Abstract (in Czech)
The analysis of potential relation between assisted reproduction teqniques (ART) and enhanced risk of ovarian carcinoma (OC) was explored by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed file includes data from 12.527 assisted reproduction treatment cycles performed at 4360 patients within years 1982-2004. After the reported malignancies number assessment from the observed group clinical database (ours and NOR) further processing, statistical analysis and results comparison was followed by the Institute of Health Information and Statistics of the Czech Republic. Statistical significance of malignancy occurance was evaluated using p-value<0.01. In the file of 4360 patients was reported 41 malignancies including 6 OC this is 3.454 times 95%CI[1.625 – 6.715] over the expected incidence to this diseased group of women. NOR offered the control diseased women group by the documented 4.236% rate among the total malignant women. It must be investigated by any reservedness whether the same risk of 3.454 developing OC exists at healthy general population women submitted to infertility treatment (p-value=0.004 Yates correction).
Abstract (in English)
The analysis of potential relation between assisted reproduction teqniques (ART) and enhanced risk of ovarian carcinoma (OC) was explored by data analysis of our University-based clinical register and National Oncology Register of Czech republic (NOR). Analyzed file includes data from 12.527 assisted reproduction treatment cycles performed at 4360 patients within years 1982-2004. After the reported malignancies number assessment from the observed group clinical database (ours and NOR) further processing, statistical analysis and results comparison was followed by the Institute of Health Information and Statistics of the Czech Republic. Statistical significance of malignancy occurance was evaluated using p-value<0.01. In the file of 4360 patients was reported 41 malignancies including 6 OC this is 3.454 times 95%CI[1.625 – 6.715] over the expected incidence to this diseased group of women. NOR offered the control diseased women group by the documented 4.236% rate among the total malignant women. It must be investigated by any reservedness whether the same risk of 3.454 developing OC exists at healthy general population women submitted to infertility treatment (p-value=0.004 Yates correction).
Links
NO7696, research and development projectName: Ovariální karcinom a léčba neplodnosti metodami in vitro fertilizace - analýza rizikových faktorů pomocí systému pro dolování znalostí z databází SHLUK a umělé neuronové sítě NEUL 3
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