C 2007

Polymorphisms in Energy Homeostasis Genes are Associated with Cutaneous T-Cell Lymphoma

BIENERTOVÁ VAŠKŮ, Julie, Vladimír VAŠKŮ, Petr BIENERT and Anna VAŠKŮ

Basic information

Original name

Polymorphisms in Energy Homeostasis Genes are Associated with Cutaneous T-Cell Lymphoma

Name in Czech

Polymorfismy v genech kontrolujících energetickou homeostázu u pacientů s kožními T-lymfomy

Authors

BIENERTOVÁ VAŠKŮ, Julie (203 Czech Republic, guarantor), Vladimír VAŠKŮ (203 Czech Republic), Petr BIENERT (203 Czech Republic) and Anna VAŠKŮ (203 Czech Republic)

Edition

New York, Tumor Markers Research Perspectives, p. 5-15, 10 pp. XX - in press, 2007

Publisher

Nova Publishers

Other information

Language

English

Type of outcome

Kapitola resp. kapitoly v odborné knize

Field of Study

30216 Dermatology and venereal diseases

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/07:00021739

Organization unit

Faculty of Medicine

ISBN

1-60021-423-1

Keywords in English

gene; cutaneous T-cell lymphoma; adipokines; leptin; adiponectin

Tags

International impact, Reviewed
Změněno: 1/7/2008 09:51, prof. MUDr. Julie Dobrovolná, Ph.D.

Abstract

V originále

In conclusion, this study suggests that genetic variation in the adiponectin and proopiomelanocortin genes may act as attractive susceptibility markers for cutaneous T-cell lymphoma (CTCL). In contrast, no association of variability in tandem region of leptin gene with CTCL has been observed. The role of the adiponectin as well as POMC as genetic markers of CTCL will require further investigation to elucidate the underlying pathophysiological consequences.

In Czech

Naše výsledky naznačují, že polymorfní oblasti v genech kontrolujících energetické hospodaření organismu (leptin, adiponektin, proopiomelanokortin) se uplatňují jako atraktivní genetické markery rizika pro kožní T-lymfom.

Links

MSM 141100002, plan (intention)
Name: Molekulární patofyziologie multigenních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Molecular pathophysiology of multigene diseases