Detailed Information on Publication Record
2006
Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo.
CURSINO, L., David ŠMAJS, Jan ŠMARDA, R.M.D. NARDI, J.R. NICOLI et. al.Basic information
Original name
Exoproducts of the strain Escherichia coli H22 inhibiting some enteric pathogens both in vitro and in vivo.
Name in Czech
Exoprodukty kmene Escherichia coli H22 inhibující některé enterální patogeny
Authors
CURSINO, L. (76 Brazil), David ŠMAJS (203 Czech Republic, guarantor), Jan ŠMARDA (203 Czech Republic), R.M.D. NARDI (76 Brazil), J.R. NICOLI (76 Brazil), E. CHARTONE-SOUZA (76 Brazil) and A.M.A. NASCIMENTO (76 Brazil)
Edition
Journal of Applied Microbiology, Oxford, UK, Blackwell Science Ltd, 2006, 1364-5072
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10600 1.6 Biological sciences
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.206
RIV identification code
RIV/00216224:14110/06:00016056
Organization unit
Faculty of Medicine
UT WoS
000236024400023
Keywords in English
bacteriophage; col-plasmid; colicin; Escherichia coli; growth inhibition; microcin
Tags
International impact, Reviewed
Změněno: 25/6/2009 15:47, prof. MUDr. David Šmajs, Ph.D.
V originále
AIMS: The antagonistic activity of the Escherichia coli strain H22 against enteric bacteria was studied both in vitro and in vivo. METHODS AND RESULTS: In vitro, bacterial strains belonging to seven of nine genera of the family Enterobacteriaceae (Enterobacter, Escherichia, Klebsiella, Morganella, Salmonella, Shigella and Yersinia) were inhibited by the strain H22. Six days after simultaneous oral inoculation in germ-free mice, E. coli strain H22 reduced the faecal population of Shigella flexneri 4 to undetectable levels (P < 0.05). In ex vivo assay, inhibitory zones against Sh. flexneri 4 were observed around faecal samples from mice inoculated with E. coli strain H22. The in vitro inhibition of Sh. flexneri 4 was shown to be mediated by microcin C7. In addition to microcin C7, strain H22 was shown to produce aerobactin, new variants of colicins E1 and Ib, and bacteriophage particles with morphology similar to the phages of the family Myoviridae. CONCLUSIONS: Altogether, the properties of E. coli H22, observed both under in vitro and in vivo conditions, suggest its potential use as a probiotic strain for livestock and humans. SIGNIFICANCE AND IMPACT OF THE STUDY: The strain H22 was shown to produce several antimicrobial compounds with inhibitory capabilities against pathogenic or potentially pathogenic enterobacteria.
In Czech
Jsou popsány a blíže studovány exoprodukty kmene Escherichia coli H22 inhibující některé enterální patogeny z celedi Enterobacteriaceae. Zejména jde o koliciny, o bakteriofágy, o korpuskulární koliciny a o siderofory.
Links
| GA310/03/1091, research and development project |
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| MSM0021622415, plan (intention) |
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