Detailed Information on Publication Record
2006
Recognition of pore-forming colicin Y by its cognate immunity protein.
ŠMAJS, David, Petra MATĚJKOVÁ and G.M. WEINSTOCKBasic information
Original name
Recognition of pore-forming colicin Y by its cognate immunity protein.
Name in Czech
Rekognice pore-forming domény kolicinu Y jeho imunitním proteinem.
Authors
ŠMAJS, David (203 Czech Republic, guarantor), Petra MATĚJKOVÁ (203 Czech Republic) and G.M. WEINSTOCK (840 United States of America)
Edition
FEMS Microbiology Letters, United Kingdom, Blackwell Publishing Ltd. 2006, 0378-1097
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10600 1.6 Biological sciences
Country of publisher
United Kingdom of Great Britain and Northern Ireland
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.068
RIV identification code
RIV/00216224:14110/06:00016068
Organization unit
Faculty of Medicine
UT WoS
000236549700018
Keywords in English
pore-forming colicin; colicin Y; colicin immunity; site-directed mutagenesis
Tags
International impact, Reviewed
Změněno: 25/6/2009 15:47, prof. MUDr. David Šmajs, Ph.D.
V originále
Construction of hybrid immunity genes between colicin U (cui) and Y (cyi) immunity genes and site-directed mutagenesis of cyi were used to identify amino-acid residues of the colicin Y immunity protein (Cyi) involved in recognition of colicin Y. These amino-acid residues were localized close to the cytoplasmic site of the Cyi transmembrane helices T3 (S104, S107, F110, A112) and T4 (A159). Mutations in cui, which converted Cui sequence to Cyi sequence in positions 104, 107, 110, 112 and 159, resulted in an immunity gene that also conferred (besides immunity to colicin U) a high degree of immunity to colicin Y.
In Czech
Je posána a diskutována rekognice pore-forming domény kolicinu Y jeho imunitním proteinem.
Links
| GA310/03/1091, research and development project |
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| MSM0021622415, plan (intention) |
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