HÁJEK, Roman, Petr KUGLÍK, Pavel NĚMEC, Romana ZAORALOVÁ, Henrieta GREŠLIKOVÁ, Hana FILKOVÁ, Renata KUPSKÁ and Gabriela PETROVIČOVÁ. Detection of chromosomal aberrations in multiple myeloma. 2006.
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Basic information
Original name Detection of chromosomal aberrations in multiple myeloma
Name in Czech Detekce chromozomových aberací u mnohočetného myelomu
Authors HÁJEK, Roman (203 Czech Republic), Petr KUGLÍK (203 Czech Republic, guarantor), Pavel NĚMEC (203 Czech Republic), Romana ZAORALOVÁ (203 Czech Republic), Henrieta GREŠLIKOVÁ (703 Slovakia), Hana FILKOVÁ (203 Czech Republic), Renata KUPSKÁ (203 Czech Republic) and Gabriela PETROVIČOVÁ (203 Czech Republic).
Edition 2006.
Other information
Original language English
Type of outcome Organization of a workshop
Field of Study Genetics and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14330/06:00017767
Organization unit Faculty of Informatics
Keywords in English Multiple myeloma; molecular cytogenetics; chromosomal aberrations; prognostic factors; FICTON
Tags chromosomal aberrations, FICTON, molecular cytogenetics, multiple myeloma, prognostic factors
Changed by Changed by: RNDr. JUDr. Vladimír Šmíd, CSc., učo 1084. Changed: 6/7/2007 11:22.
Abstract
The purpose of the workshop was the teaching of technique of light chain-specific immunofluorescent staining of clonal plasma cells and FISH analyses in multiple myeloma (MM). Immunofluorescent labelling of malignant plasma cells is suitable approach for the diagnosis of chromosomal abnormalities in patients with MM. This method allows selection of monotypic plasma cells by monoclonal antibody fluorescence (anti-kappa or anti- lambda) and detection of chromosomal abnormalities by interphase FISH (cIg FISH).
Abstract (in Czech)
Pracovní worksop zaměřeny na techniku identifikace chromozomových aberací v maligních plazmatických buňkách kostní dřeně u pacientů s mnohočetným myelomem pomocí imunofluorescenčního značení lehkých řetězců cytoplazmatických imunoglobulínů a techniky FISH
Links
LC06027, research and development projectName: Univerzitní výzkumné centrum - Česká myelomová skupina (Acronym: LC MGUS)
Investor: Ministry of Education, Youth and Sports of the CR, University Research Centre - Czech Myeloma Group
MSM0021622415, plan (intention)Name: Molekulární podstata buněčných a tkáňových regulací
Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations
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