KUČEROVÁ, Jana, Leoš LANDA, Karel ŠLAIS and Alexandra ŠULCOVÁ. Gender differences in effects of MDMA, cannabinoid agonist and their combinations in mice (Gender differences in effectS of MDMA, cannabinoid agonist and their combinations in mice.). European Neuropsychopharmacology. Amsterdam (The Netherlands): Elsevier, 2006, vol. 2006, No 16, p. 512-512. ISSN 0924-977X.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Gender differences in effects of MDMA, cannabinoid agonist and their combinations in mice
Name in Czech Mezipohlavní rozdíly v účincích extáze, kanabinoidního agonisty a jejich kombinací u myší
Authors KUČEROVÁ, Jana, Leoš LANDA, Karel ŠLAIS and Alexandra ŠULCOVÁ.
Edition European Neuropsychopharmacology, Amsterdam (The Netherlands), Elsevier, 2006, 0924-977X.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30104 Pharmacology and pharmacy
Country of publisher France
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.794
Organization unit Faculty of Medicine
UT WoS 000240771302109
Keywords in English gender differences; behavioural sensitization; mice; ecstasy; methanandamide
Tags behavioural sensitization, ecstasy, gender differences, methanandamide, mice
Tags International impact, Reviewed
Changed by Changed by: doc. PharmDr. Jana Rudá, Ph.D., učo 169493. Changed: 29/6/2009 11:47.
Abstract
The outcome of the present study showed higher susceptibility of female mice to acute MDMA administration, however the behavioural sensitization development (during the repeated treatment) and expression (caused by the challenge dose given after the drug withdrawal) were confirmed only in males. The pretreatment with cannabinoid CB1 receptor agonist led to sensitization to MDMA stimulatory effects in all animals.
Abstract (in Czech)
Prokázali jsme mnohočetné mezipohlavní rozdíly v behaviorální sensitizaci myší populace ke stimulačním účinkům extáze. U obou pohlaví se rovněž projevila zkřížená sensitizace k extázi po opakované premedikaci agonistou CB1 receptorů metanandamidem.
Links
MSM0021622404, plan (intention)Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.
PrintDisplayed: 28/4/2024 01:05