Detection of Treponema pallidum subsp. pallidum SS14 from Skin
Lesions,Serum, and CSF in an Infant with Congenital Syphilis
after Clindamycin treatment of the mother during pragnancy.

J 2007

Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin treatment of the mother during pragnancy.

WOZNICOVÁ, Vladana, David ŠMAJS, Dan WECHSLER, Magdalena FLASAROVÁ, Petra MATĚJKOVÁ et. al.

Basic information

Original name

Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin treatment of the mother during pragnancy.

Name in Czech

Detekce Treponema pallidum subsp. pallidum SS14 v kožních lezích, séru a CSF u kongenitální syfilis

Authors

WOZNICOVÁ, Vladana (203 Czech Republic, guarantor), David ŠMAJS (203 Czech Republic), Dan WECHSLER (203 Czech Republic), Magdalena FLASAROVÁ (203 Czech Republic) and Petra MATĚJKOVÁ (203 Czech Republic)

Edition

Journal of Clinical Microbiology, 2007, 0095-1137

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

10600 1.6 Biological sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.708

RIV identification code

RIV/00216224:14110/07:00019030

Organization unit

Faculty of Medicine

UT WoS

000244270000073

Keywords in English

congenital syphilis; T. p. pallidum SS14; DNA sequencing; treatment of syphilis; clindamycin

Abstract

ORIG CZ

V originále

We report a case of early congenital syphilis in a newborn after inadequate clindamycin treatment in pregnancy. Using PCR detection of tmpC (TP0319) and DNA sequencing of genes TP0136 and TP0548, DNA sequences identical to Treponema pallidum subsp. pallidum strain SS14 were detected in the infant-s skin lesions, serum, and cerebrospinal fluid.

In Czech

V práci je popisována detekce Treponema pallidum subsp. pallidum SS14 v kožních lezích, séru a CSF u kongenitální syfilis. Matka pacienta byla v těhotenství léčena clindamycinem.

Links

GA310/04/0021, research and development project

Name: Postgenomické studie syfilitické spirochety Treponema pallidum

Investor: Czech Science Foundation, Postgenomic studies on Treponema pallidum, the syphilis spirochete

MSM0021622415, plan (intention)

Name: Molekulární podstata buněčných a tkáňových regulací

Investor: Ministry of Education, Youth and Sports of the CR, Molecular basis of cell and tissue regulations

NR8967, research and development project

Name: Molekulární typizace kmenů a izolátů Treponema pallidum subsp. pallidum: základ pro epidemiologickou a klinickou identifikaci jednotlivých kmenů

Investor: Ministry of Health of the CR

Citovat

WOZNICOVÁ, Vladana, David ŠMAJS, Dan WECHSLER, Magdalena FLASAROVÁ and Petra MATĚJKOVÁ. Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin treatment of the mother during pragnancy. (Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin.). Journal of Clinical Microbiology. 2007, vol. 2007, No 45, p. 659-661. ISSN 0095-1137.

@article{704283,
   author = {Woznicová, Vladana and Šmajs, David and Wechsler, Dan and Flasarová, Magdalena and Matějková, Petra},
   article_number = {45},
   keywords = {congenital syphilis; T. p. pallidum SS14; DNA sequencing; treatment of syphilis; clindamycin},
   language = {eng},
   issn = {0095-1137},
   journal = {Journal of Clinical Microbiology},
   title = {Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin treatment of the mother during pragnancy.},
   volume = {2007},
   year = {2007}
}

TY  - JOUR
ID  - 704283
AU  - Woznicová, Vladana - Šmajs, David - Wechsler, Dan - Flasarová, Magdalena - Matějková, Petra
PY  - 2007
TI  - Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin treatment of the mother during pragnancy.
JF  - Journal of Clinical Microbiology
VL  - 2007
IS  - 45
SP  - 659-661
EP  - 659-661
SN  - 00951137
KW  - congenital syphilis
KW  - T. p. pallidum SS14
KW  - DNA sequencing
KW  - treatment of syphilis
KW  - clindamycin
N2  - We report a case of early congenital syphilis in a newborn after inadequate clindamycin treatment in pregnancy. Using PCR detection of tmpC (TP0319) and DNA sequencing of genes TP0136 and TP0548, DNA sequences identical to Treponema pallidum subsp. pallidum strain SS14 were detected in the infant-s skin lesions, serum, and cerebrospinal fluid.
ER  -

WOZNICOVÁ, Vladana, David ŠMAJS, Dan WECHSLER, Magdalena FLASAROVÁ and Petra MATĚJKOVÁ. Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin treatment of the mother during pragnancy. (Detection of Treponema pallidum subsp. pallidum SS14 from Skin Lesions,Serum, and CSF in an Infant with Congenital Syphilis after Clindamycin.). \textit{Journal of Clinical Microbiology}. 2007, vol.~2007, No~45, p.~659-661. ISSN~0095-1137.

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