SOUČEK, Miroslav, Ivan ŘIHÁČEK and Petr FRÁŇA. A comparison of the trough-peak ratio of cardio-selective beta-blockers in patients with newly diagnosed hypertension. Blood pressure monitoring. Londýn: Lippincott, Williams and Wilkins, 2006, vol. 11, No 6, p. 337-342. ISSN 1359-5237.
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Basic information
Original name A comparison of the trough-peak ratio of cardio-selective beta-blockers in patients with newly diagnosed hypertension.
Name in Czech Srovnání trough-peak poměru kardioselektivních beta-blokátorů u pacientů s čerstvě zjištěnou hypertenzí.
Name (in English) A comparison of the trough-peak ratio of cardio-selective beta-blockers in patients with newly diagnosed hypertension.
Authors SOUČEK, Miroslav (203 Czech Republic), Ivan ŘIHÁČEK (203 Czech Republic, guarantor) and Petr FRÁŇA (203 Czech Republic).
Edition Blood pressure monitoring, Londýn, Lippincott, Williams and Wilkins, 2006, 1359-5237.
Other information
Original language Czech
Type of outcome Article in a journal
Field of Study 30201 Cardiac and Cardiovascular systems
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.424
RIV identification code RIV/00216224:14110/06:00017798
Organization unit Faculty of Medicine
Keywords in English blood pressure monitoring;hypertension;trough-to-peak ratio;beta-blockers.
Tags beta-blockers., blood pressure monitoring, Hypertension, trough-to-peak ratio
Tags International impact, Reviewed
Changed by Changed by: MUDr. Ivan Řiháček, Ph.D., učo 2313. Changed: 8/12/2006 15:03.
Abstract
The drug can be administered once a day, if the tough-to-peak ratio (T/P) exceeds 50-66%. The mean T/P of betaxolol hydrochloride was calculated 72,84 +- 33,32% (95% CI, 60,40-85,28%) for systolic BP and 71,57 +-29,35% (95% CI, 60,62-82,53%) for diastolic BP. The mean T/P of metoprolol tartrate was calculated 70,59 +- 31,66% (95% CI, 58,76-82,41%) fo systolic BP and 66,95 +- 31,60% (95% CI, 55,15-78,75%) for diastolic BP. 95% CI - 95% confidence interval. Conclusion: The T/P ratio determined for betaxolol hydrochloride and metoprolol tartrate is higher than 66%. The ratio garatees a satisfactory 24-h effect of both the above mentioned drugs.
Abstract (in English)
The drug can be administered once a day, if the tough-to-peak ratio (T/P) exceeds 50-66%. The mean T/P of betaxolol hydrochloride was calculated 72,84 +- 33,32% (95% CI, 60,40-85,28%) for systolic BP and 71,57 +-29,35% (95% CI, 60,62-82,53%) for diastolic BP. The mean T/P of metoprolol tartrate was calculated 70,59 +- 31,66% (95% CI, 58,76-82,41%) fo systolic BP and 66,95 +- 31,60% (95% CI, 55,15-78,75%) for diastolic BP. 95% CI - 95% confidence interval. Conclusion: The T/P ratio determined for betaxolol hydrochloride and metoprolol tartrate is higher than 66%. The ratio garatees a satisfactory 24-h effect of both the above mentioned drugs.
Links
MSM0021622402, plan (intention)Name: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases
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