The subjects treated for a malignant tumour by anthracyclines in comparison to healthy controls and subjects treated for a tumour without anthracyclines had increased parasympathetic and decreased sympathetic tonic activity as was documented by lower systolic blood pressure and higher baroreflex sensitivity. The increase of parasympathetic reflex control of the heart after antitumour therapy is not a sign of physical training as it is seen in healthy population, but rather could be a consequence of cardiotoxic and neurotoxic therapy or of a disease.
In English
The subjects treated for a malignant tumour by anthracyclines in comparison to healthy controls and subjects treated for a tumour without anthracyclines had increased parasympathetic and decreased sympathetic tonic activity as was documented by lower systolic blood pressure and higher baroreflex sensitivity. The increase of parasympathetic reflex control of the heart after antitumour therapy is not a sign of physical training as it is seen in healthy population, but rather could be a consequence of cardiotoxic and neurotoxic therapy or of a disease.
Links
MSM0021622402, plan (intention)
Name: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases
NR8006, research and development project
Name: Autonomní oběhové funkce, funkce myokardu a kardiorespirační funkce u dětí a adolescentů po léčbě zhoubného nádoru