Detailed Information on Publication Record
2006
The associations between MHC genes and metazoan parasites in the fish populations living under the different level of environmental pollution
ŠIMKOVÁ, Andrea, Martina PEČÍNKOVÁ, Barbora BÍMOVÁ and Peter MIKULÍČEKBasic information
Original name
The associations between MHC genes and metazoan parasites in the fish populations living under the different level of environmental pollution
Name in Czech
Vztah mezi MHC geny a rybími mnohobuněčnými parazity v odlišných environmentálních podmínkách
Authors
ŠIMKOVÁ, Andrea (203 Czech Republic, guarantor), Martina PEČÍNKOVÁ (203 Czech Republic), Barbora BÍMOVÁ (203 Czech Republic) and Peter MIKULÍČEK (703 Slovakia)
Edition
Windhoek, Namibie, The 35th Annual Congress of the Parasitological Society of Southern Africa, Windhoek (Namibia), Book of Abstracts, p. 23-23, 2006
Publisher
Department of Biology, University of Namibia, Windhoek, Namibia
Other information
Language
English
Type of outcome
Stať ve sborníku
Field of Study
10600 1.6 Biological sciences
Country of publisher
Namibia
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/06:00016154
Organization unit
Faculty of Science
Keywords in English
MHC genes;fish;parasite
Tags
International impact
Změněno: 8/1/2007 19:38, prof. RNDr. Andrea Vetešníková Šimková, PhD.
V originále
The major histocompatibility complex (MHC) represents a group of genes of the highly polymorphic loci encoding the proteins that bind a peptide fragments derived from the foreign antigens and stimulate an immune response. The specific role of MHC as a mediator of the adaptive immune response suggests that the MHC profile could reflect the effects of environmental changes connected with chemical pollution as well as the indirect parasite-mediated selection. However, until now MHC variation has not been often used in the pollutant assays. In our study we tested whether the immunogenetic profiles measured by nucleotide and amino-acid substitutions in MHC class IIB (DAB genes) predominantly in peptide-binding regions vary between fish populations living under conditions of different environmental stress and parasite pressure. In the freshwater fish gudgeon, Gobio gobio, three populations collected from the localities differing by the environmental pollution (heavy metals and persistent organic pollutants) were studied. Fish were investigated for all metazoan parasites and the representatives of Monogenea, Digenea, Cestoda and Acanthocephala were recorded. The differences in presence or absence of the metazoan parasite species were observed as well as the parasite intensity infection was different when comparing three localities. Moreover, the different composition of parasite communities was observed concerning the proportions of specialist and generalist parasites. Even several MHC haplotypes were shared between populations, the specific alleles (or the specific nucleotide or amino-acid motives within alleles) were observed in each locality. The relationships between parasitism and MHC diversity in the association with different level of environmental pollution were analyzed and discussed.
In Czech
The major histocompatibility complex (MHC) represents a group of genes of the highly polymorphic loci encoding the proteins that bind a peptide fragments derived from the foreign antigens and stimulate an immune response. The specific role of MHC as a mediator of the adaptive immune response suggests that the MHC profile could reflect the effects of environmental changes connected with chemical pollution as well as the indirect parasite-mediated selection. However, until now MHC variation has not been often used in the pollutant assays. In our study we tested whether the immunogenetic profiles measured by nucleotide and amino-acid substitutions in MHC class IIB (DAB genes) predominantly in peptide-binding regions vary between fish populations living under conditions of different environmental stress and parasite pressure. In the freshwater fish gudgeon, Gobio gobio, three populations collected from the localities differing by the environmental pollution (heavy metals and persistent organic pollutants) were studied. Fish were investigated for all metazoan parasites and the representatives of Monogenea, Digenea, Cestoda and Acanthocephala were recorded. The differences in presence or absence of the metazoan parasite species were observed as well as the parasite intensity infection was different when comparing three localities. Moreover, the different composition of parasite communities was observed concerning the proportions of specialist and generalist parasites. Even several MHC haplotypes were shared between populations, the specific alleles (or the specific nucleotide or amino-acid motives within alleles) were observed in each locality. The relationships between parasitism and MHC diversity in the association with different level of environmental pollution were analyzed and discussed.
Links
| GA524/04/1128, research and development project |
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| MSM0021622416, plan (intention) |
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