Změna behaviorálního efektu metamfetaminu po opakovaném podání extáze u myší
LANDA, Leoš, Karel ŠLAIS and Alexandra ŠULCOVÁ. Změna behaviorálního efektu metamfetaminu po opakovaném podání extáze u myší (Change of the behavioural methamphetamine effect after repeated ecstasy administration in mice). 2007. |
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Basic information | |
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Original name | Změna behaviorálního efektu metamfetaminu po opakovaném podání extáze u myší |
Name in Czech | Změna behaviorálního efektu metamfetaminu po opakovaném podání extáze u myší |
Name (in English) | Change of the behavioural methamphetamine effect after repeated ecstasy administration in mice |
Authors | LANDA, Leoš (203 Czech Republic, guarantor), Karel ŠLAIS (203 Czech Republic) and Alexandra ŠULCOVÁ (203 Czech Republic). |
Edition | 2007. |
Other information | |
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Original language | Czech |
Type of outcome | Conference abstract |
Field of Study | 30104 Pharmacology and pharmacy |
Country of publisher | Czech Republic |
Confidentiality degree | is not subject to a state or trade secret |
RIV identification code | RIV/00216224:14110/07:00021855 |
Organization unit | Faculty of Medicine |
Keywords in English | behavioural sensitization; methamphetamine; ecstasy; mice |
Tags | behavioural sensitization, ecstasy, methamphetamine, mice |
Changed by | Changed by: MUDr. Mgr. Karel Šlais, Ph.D., učo 19989. Changed: 31/3/2010 11:37. |
Abstract |
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Objevil se signifikantní nárust aktivity po akutní dávce extáze; nedošlo k žádnému rozvoji ani expresi sensitizace po opakovaném podávání extáze; došlo k signifikantnímu nárustu aktivity po akutní dávce metamfetaminu a objevil se rozvoj i exprese sensitizace k extázi po opakovaném podávání metamfetaminu. Zkřížená sensitizace k extázi po opakovaném podání metamfetaminu se nevyskytla. |
Abstract (in English) |
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The results showed significant stimulatory influence of ecstasy after the acute administration; neither development nor expression of sensitization after ecstasy repeated treatment; significant stimulatory influence of methamphetamine after the acute administration and both development and expression of sensitization after methamphetamine repeated treatment; development and expression of cross-sensitization following methamphetamine challenge dose after ecstasy pre-treatment. Finally, no cross-sensitization was registered following ecstasy challenge dose after methamphetamine pre-treatment. |
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MSM0021622404, plan (intention) | Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS |
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions. |
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