a 2006

Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus

KOBETIČOVÁ, Klára, Jakub HOFMAN and Ivan HOLOUBEK

Basic information

Original name

Comparison of toxic effects of PAHs and their N-heterocyclic analogues to enchytraeid Enchytraeus crypticus

Name in Czech

Efekty PAHs a jejich N-heterocyklických analogů na roupici Enchytraeus crypticus

Authors

KOBETIČOVÁ, Klára (203 Czech Republic), Jakub HOFMAN (203 Czech Republic, guarantor) and Ivan HOLOUBEK (203 Czech Republic)

Edition

Abstract Book of SETAC Europe the 16th Annual Meeting, 2006

Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

10511 Environmental sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/06:00016309

Organization unit

Faculty of Science

Keywords in English

ecotoxicology; azaPAHs; soil

Tags

International impact
Změněno: 24/2/2010 22:31, prof. RNDr. Jakub Hofman, Ph.D.

Abstract

V originále

Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both by individual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 525/04/P159

In Czech

Polycyclic aromatic hydrocarbons and their N-heterocycles (azaPAHs) are ubiquitous environmental pollutants and they are frequently present in contaminated soils. The aim of this study was compared the toxic effects of some two- and three-ringed PAHs (naphthalene, phenanthrene, anthracene) and their N-heterocyclic analogues with one (quinoline, acridine, phenanthridine) or two (quinoxaline, phenazine, 1,10-phenanthroline) nitrogen atoms on Enchytraeus crypticus survival and reproduction in OECD artificial soil test. The results did not indicate clear relationships between the toxicity and chemical structure of compounds. However, some trends were apparent and a kind of "pseudo-QSAR" might be possible. The final toxic effect in soil was affected both by individual compound fate in soil (bioavailability) and by specific mode of action to E.crypticus. Both these components must be included in the QSAR calculation in the soil. This research was supported by Grant Agency of Czech Republic 525/04/P159

Links

GP525/04/P159, research and development project
Name: Vliv nově rozpoznávaných prioritních perzistentních organických polutantů (POPs) na organismy v půdním ekosystému
Investor: Czech Science Foundation, Effects of newly recognized priority persistent organic pollutants (POPs) on organisms of soil ecosystem
MSM0021622412, plan (intention)
Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL)
Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)