J 2006

Correlation of Expression of Ki-67, EGFR, c-erbB-2,MMP-9, p53, bcl-2, CD34 and Cell Cycle Analysis with Survival in Head and Neck Squamous Cell Cancer

SMILEK, Pavel, Ladislav DUŠEK, Karel VESELÝ, Jan ROTTENBERG, Rom KOSTŘICA et. al.

Basic information

Original name

Correlation of Expression of Ki-67, EGFR, c-erbB-2,MMP-9, p53, bcl-2, CD34 and Cell Cycle Analysis with Survival in Head and Neck Squamous Cell Cancer

Name in Czech

Korelace exprese Ki-67, EGFR, c-erbB-2,MMP-9, p53, bcl-2, CD34 a analýzy buněčného cyklu s přežitím u karcinomů hlavy a krku

Name (in English)

Correlation of Expression of Ki-67, EGFR, c-erbB-2,MMP-9, p53, bcl-2, CD34 and Cell Cycle Analysis with Survival in Head and Neck Squamous Cell Cancer

Authors

SMILEK, Pavel (203 Czech Republic, guarantor), Ladislav DUŠEK (203 Czech Republic), Karel VESELÝ (203 Czech Republic), Jan ROTTENBERG (203 Czech Republic) and Rom KOSTŘICA (203 Czech Republic)

Edition

Journal of Experimental & Clinical Cancer Research, Rome, Italy, Regina Elena Institute, 2006, 0392-9078

Other information

Language

Czech

Type of outcome

Článek v odborném periodiku

Field of Study

30200 3.2 Clinical medicine

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.869

RIV identification code

RIV/00216224:14110/06:00018469

Organization unit

Faculty of Medicine

UT WoS

000243734200014

Keywords in English

Head and neck cancer; mitotic index;bcl-2;DNA cytometry

Tags

International impact, Reviewed
Změněno: 7/7/2009 13:16, doc. MUDr. Pavel Smilek, Ph.D.

Abstract

V originále

The analysis of the set of 217 patients suffering from head and neck carcinoma was done. Cytokinetic parameters strongly correlated with grade score.Positivity in bcl-2, and MMP-9 was related to OS. Positivity of EGFR, C-erbB-2, CD34, p53 did not reached statistically significant value in association to EFS or OS.

In English

The analysis of the set of 217 patients suffering from head and neck carcinoma was done. Cytokinetic parameters strongly correlated with grade score.Positivity in bcl-2, and MMP-9 was related to OS. Positivity of EGFR, C-erbB-2, CD34, p53 did not reached statistically significant value in association to EFS or OS.

Links

MSM 141100003, plan (intention)
Name: Zevní prostředí - karcinogeneze - onkologie
Investor: Ministry of Education, Youth and Sports of the CR, Environment - carcinogenesis - oncology