Detailed Information on Publication Record
2007
Low-frequency magnetic field effect on cytoskeleton and chromatin
KROUPOVÁ, Jana, Eva BÁRTOVÁ, Lukáš FOJT, Luděk STRAŠÁK, Stanislav KOZUBEK et. al.Basic information
Original name
Low-frequency magnetic field effect on cytoskeleton and chromatin
Name in Czech
Vliv nízkofrekvenčního magnetického pole na cytoskelet a chromatin.
Authors
KROUPOVÁ, Jana, Eva BÁRTOVÁ, Lukáš FOJT, Luděk STRAŠÁK, Stanislav KOZUBEK and Vladimír VETTERL
Edition
Bioelectrochemistry, Elsevier, 2007, 1567-5394
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
10610 Biophysics
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 2.992
Organization unit
Faculty of Medicine
UT WoS
000243708600018
Keywords in English
ELF; low-frequency magnetic field; cytosceleton; chromatin; apoptosis;
Tags
International impact, Reviewed
Změněno: 27/1/2007 17:20, prof. RNDr. Vladimír Vetterl, DrSc.
V originále
We studied low-frequency magnetic field effect on cytoskeleton and on the structure of chromatin in human cells. We used cell line of small lung carcinoma (A549) and the effects of magnetic field on cytoskeleton and higher-order chromatin structure were analyzed 96 h of magnetic field exposure. Magnetic field induction was Bm = 2 mT and the net frequency f = 50 Hz. In such affected and control cells the F-actin was estimated using FITC-conjugated Phalloidin and mitochondria were studied using MitoTracker (Molecular Probes). Images of cytoskeleton and genetic loci were acquired using confocal microscopy and analysis was performed by FISH 2.0 software. Slight morphological changes of F-actin filaments and mitochondria were observed in affected cells and nuclear condensation was found.
In Czech
Byl sledován vliv magnetického pole o frekvenci 50 Hz na cytoskelet a chromatin buněk plicního karcinomu A549. Byly pozorovány malé morfologické změny vláken F-actinu a mitochondrií.
Links
| IAA4004702, research and development project |
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| IBS5004107, research and development project |
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