KROUPOVÁ, Jana, Eva BÁRTOVÁ, Lukáš FOJT, Luděk STRAŠÁK, Stanislav KOZUBEK and Vladimír VETTERL. Low-frequency magnetic field effect on cytoskeleton and chromatin. Bioelectrochemistry. Elsevier, 2007, vol. 70, No 1, p. 96-100. ISSN 1567-5394.
Other formats:   BibTeX LaTeX RIS
Basic information
Original name Low-frequency magnetic field effect on cytoskeleton and chromatin
Name in Czech Vliv nízkofrekvenčního magnetického pole na cytoskelet a chromatin.
Authors KROUPOVÁ, Jana, Eva BÁRTOVÁ, Lukáš FOJT, Luděk STRAŠÁK, Stanislav KOZUBEK and Vladimír VETTERL.
Edition Bioelectrochemistry, Elsevier, 2007, 1567-5394.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10610 Biophysics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.992
Organization unit Faculty of Medicine
UT WoS 000243708600018
Keywords in English ELF; low-frequency magnetic field; cytosceleton; chromatin; apoptosis;
Tags apoptosis, chromatin, cytosceleton, ELF, low-frequency magnetic field
Tags International impact, Reviewed
Changed by Changed by: prof. RNDr. Vladimír Vetterl, DrSc., učo 1954. Changed: 27/1/2007 17:20.
Abstract
We studied low-frequency magnetic field effect on cytoskeleton and on the structure of chromatin in human cells. We used cell line of small lung carcinoma (A549) and the effects of magnetic field on cytoskeleton and higher-order chromatin structure were analyzed 96 h of magnetic field exposure. Magnetic field induction was Bm = 2 mT and the net frequency f = 50 Hz. In such affected and control cells the F-actin was estimated using FITC-conjugated Phalloidin and mitochondria were studied using MitoTracker (Molecular Probes). Images of cytoskeleton and genetic loci were acquired using confocal microscopy and analysis was performed by FISH 2.0 software. Slight morphological changes of F-actin filaments and mitochondria were observed in affected cells and nuclear condensation was found.
Abstract (in Czech)
Byl sledován vliv magnetického pole o frekvenci 50 Hz na cytoskelet a chromatin buněk plicního karcinomu A549. Byly pozorovány malé morfologické změny vláken F-actinu a mitochondrií.
Links
IAA4004702, research and development projectName: Adsorpce bazí, nukleosidů, nukleotidů a polynukleotidů na elektrodách
Investor: Academy of Sciences of the Czech Republic, Adsorption of bases, nucleosides, nucleotides and polynucleotides on electrods
IBS5004107, research and development projectName: Aplikace biofyzikálních metod v biotechnologické a klinické praxi
Investor: Academy of Sciences of the Czech Republic, Application of biophysical methods in biotechnological and clinical praxis
PrintDisplayed: 25/4/2024 09:34