Double elimination of oligonucleotides

MIKELOVÁ, Radka, Libuše TRNKOVÁ and František JELEN. Double elimination of oligonucleotides. In Sborník příspěvků VII. Pracovního setkání fyzikálních chemiků a elektrochemiků. Brno: Masarykova universita, 2007, p. 99-101. ISBN 9788021042353.

Basic information

Original name

Double elimination of oligonucleotides

Name in Czech

Dvojnásobná eliminace oligonukleotidů

Authors

MIKELOVÁ, Radka (203 Czech Republic), Libuše TRNKOVÁ (203 Czech Republic, guarantor) and František JELEN (203 Czech Republic)

Edition

Brno, Sborník příspěvků VII. Pracovního setkání fyzikálních chemiků a elektrochemiků, p. 99-101, 3 pp. 2007

Publisher

Masarykova universita

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Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10405 Electrochemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14310/07:00019364

Organization unit

Faculty of Science

ISBN

9788021042353

Keywords in English

Elimination voltammetry; Double elimination voltammetry;electrochemistry; Oligonucleotides

Tags

double elimination voltammetry, electrochemistry, Elimination voltammetry, Oligonucleotides

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Abstract

V originále

Ten years ago the theory of elimination voltammetry with linear scan (EVLS) was published and experimentally verified for reversible, quasi-reversible and irreversible electrode systems1-3. The EVLS can be considered a mathematical model of the transformation of current-potential curves capable of eliminating some selected current components, and conserving the other ones. This contribution is devoted to the EVLS transformation of irreversible current-potential curves of an adsorbed electroactive substance. The function eliminating charging and kinetic current components, and conserving the diffusion current component, yields specific, sensitive and well developed peak-couterpeak (p-cp) signal3-5. Theoretical value of ratio Ip/(Ip+Icp) is 0,40973,5,8. This signal was successfully employed in the analysis of nucleic acids and short homo- or hetero-deoxyoligonucleotides (ODNs) containing adenine (A) and cytosine (C)4-12.

In Czech

Double eliminace oligonukleotidů

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Links

IAA100040602, research and development project	Name: Nové přístupy v elektrochemické analýze nukleových kyselin a oligonukleotidů zaměřené na ultrasensitivní mikrodetekci DNA a detekci DNA hybridizace. Investor: Academy of Sciences of the Czech Republic, New approaches in electrochemical analysis of nucleic acids and oligonucleotides aimed at a ultrasensitive microdetection of DNA and DNA hybridization
LC06035, research and development project	Name: Centrum biofyzikální chemie, bioelektrochemie a bioanalýzy. Nové nástroje pro genomiku, proteomiku a biomedicínu. Investor: Ministry of Education, Youth and Sports of the CR, Centre of Biophysical Chemistry, Bioelectrochemistry and Bioanalysis. New Tools for Genomics, Proteomics and Biomedicine
MSM0021622412, plan (intention)	Name: Interakce mezi chemickými látkami, prostředím a biologickými systémy a jejich důsledky na globální, regionální a lokální úrovni (INCHEMBIOL) (Acronym: INCHEMBIOL) Investor: Ministry of Education, Youth and Sports of the CR, Interactions among the chemicals, environment and biological systems and their consequences on the global, regional and local scales (INCHEMBIOL)