J 2005

The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: evidence from the results of an open, prospective, one-year trial

POHANKA, Michal, Petr KAŇOVSKÝ, Martin BAREŠ, Jiří PULKRÁBEK, Ivan REKTOR et. al.

Basic information

Original name

The long-lasting improvement of sexual dysfunction in patients with advanced, fluctuating Parkinson's disease induced by pergolide: evidence from the results of an open, prospective, one-year trial

Name in Czech

Dlouhodobé zlepšení sexuální dysfunkce u pacientů s pokročilou Parkinsonovou nemocí navozené podáváním pergolidu

Authors

POHANKA, Michal (203 Czech Republic), Petr KAŇOVSKÝ (203 Czech Republic, guarantor), Martin BAREŠ (203 Czech Republic), Jiří PULKRÁBEK (203 Czech Republic) and Ivan REKTOR (203 Czech Republic)

Edition

Parkinsonism and Related Disorders, Oxford, Elsevier, 2005, 1353-8020

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.527

RIV identification code

RIV/00216224:14110/05:00031905

Organization unit

Faculty of Medicine

UT WoS

000233791000006

Keywords in English

Parkinson disease; pergolid; sexual dysfunction

Tags

International impact, Reviewed
Změněno: 31/3/2010 23:28, prof. MUDr. Martin Bareš, Ph.D.

Abstract

V originále

Fourteen male patients suffering from Parkinson's disease, each of whom had been treated with L-DOPA, and in whom additional treatment with oral dopamine agonist (DA) was needed, were followed for a period of one year. Pergolide mesylate was given to each patient, and titrated to a total daily dose of 3 mg. All of the patients were taking L-DOPA. The assessments consisted of neurological examination, unified Parkinson's disease rating scale (UPDRS) III and IV subscales scoring, mini mental state examination (MMSE) scoring, the neuropsychological examination, biochemical and hematological examinations and a sexological examination during which the patients filled-in the international index of erectile function (IIEF) questionnaire. Pergolide mesylate significantly improved all sexual functions in younger male Parkinsonian patients who were still interested in sexual activities.

In Czech

Dlouhodobé zlepšení sexuální dysfunkce u pacientů s pokročilou Parkinsonovou nemocí navozené podáváním pergolidu.

Links

MSM0021622404, plan (intention)
Name: Vnitřní organizace a neurobiologické mechanismy funkčních systémů CNS
Investor: Ministry of Education, Youth and Sports of the CR, The internal organisation and neurobiological mechanisms of functional CNS systems under normal and pathological conditions.