Neopterin and oxidative stress in patients with heart failure

D 2007

Neopterin and oxidative stress in patients with heart failure

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ et. al.

Basic information

Original name

Neopterin and oxidative stress in patients with heart failure

Name in Czech

Neopterin a oxidační stres u pacientů se srdečním selháním

Authors

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ and Jindřich ŠPINAR

Edition

1. vyd. Bratislava, Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention. p. 97-97, 1 pp. 2007

Publisher

Mind and Helth, civil association

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Slovakia

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Medicine

ISBN

978-80-969663-2-5

Keywords in English

heart failure; oxidative stress; neopterin; cell-mediated immunity

Abstract

ORIG CZ

V originále

Recent data suggest among others that inflammation and oxidative stress may be associated with the development of heart failure. Neopterin is a sensitive marker for disease involving activated cell-mediated immune system in humans and besides induce oxidative stress in vitro. The aim of our study was to determine neopterin levels in patients with acute myocardial infarction (AMI) and chronic heart failure (CHF) and find a possible relationship with parameters of oxidative stress. The results of our study confirm an existence of T-lymphocyte activation, more in patients with ischemic origin of heart failure than cardiomyopathy. Moreover, cell-mediated activation of immune system might be independent on the time of progression of ischemic heart failure.

In Czech

The results of our study confirm an existence of T-lymphocyte activation, more in patients with ischemic origin of heart failure than cardiomyopathy. Moreover, cell-mediated activation of immune system might be independent on the time of progression of ischemic heart failure.

Links

MSM0021622402, plan (intention)

Name: Časná diagnostika a léčba kardiovaskulárních chorob

Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases

Citovat

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ and Jindřich ŠPINAR. Neopterin and oxidative stress in patients with heart failure. In Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention. 1st ed. Bratislava: Mind and Helth, civil association, 2007, p. 97-97. ISBN 978-80-969663-2-5.

@inproceedings{716014,
   author = {Tomandl, Josef and Pařenica, Jiří and Táborská, Eva and Špinarová, Lenka and Čermáková, Zdeňka and Špinar, Jindřich},
   address = {Bratislava},
   booktitle = {Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention.},
   edition = {1.},
   keywords = {heart failure; oxidative stress; neopterin; cell-mediated immunity},
   language = {eng},
   location = {Bratislava},
   isbn = {978-80-969663-2-5},
   pages = {97-97},
   publisher = {Mind and Helth, civil association},
   title = {Neopterin and oxidative stress in patients with heart failure},
   year = {2007}
}

TY  - JOUR
ID  - 716014
AU  - Tomandl, Josef - Pařenica, Jiří - Táborská, Eva - Špinarová, Lenka - Čermáková, Zdeňka - Špinar, Jindřich
PY  - 2007
TI  - Neopterin and oxidative stress in patients with heart failure
PB  - Mind and Helth, civil association
CY  - Bratislava
SN  - 9788096966325
KW  - heart failure
KW  - oxidative stress
KW  - neopterin
KW  - cell-mediated immunity
N2  - Recent data suggest among others that inflammation and oxidative stress may be associated with the development of heart failure. Neopterin is a sensitive marker for disease involving activated cell-mediated immune system in humans and besides induce oxidative stress in vitro. The aim of our study was to determine neopterin levels in patients with acute myocardial infarction (AMI) and chronic heart failure (CHF) and find a possible relationship with parameters of oxidative stress. The results of our study confirm an existence of T-lymphocyte activation, more in patients with ischemic origin of heart failure than cardiomyopathy. Moreover, cell-mediated activation of immune system might be independent on the time of progression of ischemic heart failure.
ER  -

TOMANDL, Josef, Jiří PAŘENICA, Eva TÁBORSKÁ, Lenka ŠPINAROVÁ, Zdeňka ČERMÁKOVÁ and Jindřich ŠPINAR. Neopterin and oxidative stress in patients with heart failure. In \textit{Book of abstracts from the conference Synthetic and natural compounds in cancer therapy and prevention.}. 1st ed. Bratislava: Mind and Helth, civil association, 2007, p.~97-97. ISBN~978-80-969663-2-5.

Detailed Information on Publication Record