D 2006

Voltage homogenity over the membrane of cardiac cell with a transverse-axial tubular system

CHRISTÉ, Georges, Michal PÁSEK and Jiří ŠIMURDA

Basic information

Original name

Voltage homogenity over the membrane of cardiac cell with a transverse-axial tubular system

Name in Czech

Napěťová homogenita na membráně srdeční buňky s transverzálně-axiálním tubulárním systémem

Authors

CHRISTÉ, Georges, Michal PÁSEK and Jiří ŠIMURDA

Edition

Brno, Analysis of Biomedical Signals and Images, p. 333-335, 2006

Publisher

VUTIUM Press

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10610 Biophysics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Organization unit

Faculty of Medicine

ISBN

80-214-3152-0

Keywords in English

cardiac myocytes; voltage homogenity; mathematical model

Tags

International impact, Reviewed
Změněno: 18/4/2007 18:11, doc. Ing. Michal Pásek, Ph.D.

Abstract

V originále

The surface membrane of cardiac ventricular myocytes has a complex system of invaginations known as the transverse-axial tubular system (TATS). In order to evaluate the functional importance of the TATS, one question to address is whether the surface and tubular transmembrane voltages differ at rest and during activity. We present here the theoretical background of the passive electrical properties of the interconnected ensemble formed with the surface membrane and the TATS membrane, the latter being simplified to a single compartment. We compare its behaviour with that of our model of ventricular cardiac myocyte with TATS. We conclude that both membrane compartments behave as a homogeneous electrical whole.

In Czech

Práce se zabývá vyšetřením úrovně napěťové homogenity mezi povrchovou a tubulární membránou u srdečních komorových buněk. Vyšetření je provedeno na matematickém modelu.

Links

MSM0021622402, plan (intention)
Name: Časná diagnostika a léčba kardiovaskulárních chorob
Investor: Ministry of Education, Youth and Sports of the CR, Early diagnostics and treatment of cardiovascular diseases