Detailed Information on Publication Record
2006
Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?
ZÁVODNÁ, Eva, Nataša HONZÍKOVÁ, Hana HRSTKOVÁ, Zuzana NOVÁKOVÁ, Jiří MOUDR et. al.Basic information
Original name
Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?
Name in Czech
Je možno detekovat vývoj citlivosti baroreflexu u člověka ve věku 11 až 20 let?
Authors
ZÁVODNÁ, Eva (203 Czech Republic, guarantor, belonging to the institution), Nataša HONZÍKOVÁ (203 Czech Republic, belonging to the institution), Hana HRSTKOVÁ (203 Czech Republic, belonging to the institution), Zuzana NOVÁKOVÁ (203 Czech Republic, belonging to the institution), Jiří MOUDR (203 Czech Republic, belonging to the institution), Miroslav JÍRA (203 Czech Republic, belonging to the institution) and Bohumil FIŠER (203 Czech Republic, belonging to the institution)
Edition
Canadian Journal of Physiology and Pharmacology, Ottawa, Canada, National Research Council of Canada, 2006, 0008-4212
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30105 Physiology
Country of publisher
Canada
Confidentiality degree
není předmětem státního či obchodního tajemství
References:
Impact factor
Impact factor: 1.380
RIV identification code
RIV/00216224:14110/06:00018695
Organization unit
Faculty of Medicine
UT WoS
000245407900007
Keywords in English
baroreflex sensitivity; spectral analysis; age; adolescents; children
Tags
International impact, Reviewed
Změněno: 10/7/2015 17:00, Ing. Mgr. Věra Pospíšilíková
V originále
The aim of the study was to determine changes of baroreflex sensitivity (BRS/BRSf) in humans between 11 and 20 years of age. Beat-by-beat values of inter-beat intervals (IBI) or heart rate, and systolic and diastolic blood pressures were measured for 5 min in 415 healthy subjects. BRS did not correlate with age, but BRSf significantly decreased (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Results of multiregression equations were: BRS=1.37-0.56*age+0.02*IBI (p<0.001 for BRS vs. age and for BRS vs. IBI); BRSf=34.74–0.97*age-0.001*IBI (p<0.001 only for BRS vs. age). The limits of BRS: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.7, and limits for BRSf: 5th percentile - 8.5 mHz/mmHg; 50th - 16.4; 95th - 33.6. Conclusion: IBI-dependent BRS was unchanged in the particular age groups, but the standardization of BRS on IBI was decreased with age. BRSf was IBI-independent and better reflected the development of the baroreflex sensitivity.
In Czech
Cílem práce bylo ukázat vývoj citlivosti baroreflexu (BRS[ms/mmHg]/BRSf[mHz/mmHg]) u člověka ve věku 11 – 20 let. U 415 zdravých osob byly po dobu 5 min. zaznamenávány tep po tepu hodnoty srdečních intervalů (SI), popř. srdeční frekvence, systolického a diastolického tlaku. BRS nekorelovalo s věkem, naopak BRSf s věkem významně klesalo (p<0.001). BRS korelovalo významně s SI (p<0.001), ale BRSf bylo na IBI nezávislé. Výsledky multiregresní analýzy: BRS=1,37-0,56*věk+0,02*SI (p<0.001 pro BRS vs. věk a pro BRS vs. SI); BRSf=34,74–0,97*věk-0.001*SI (p<0.001 pouze pro BRS vs. věk). Limity BRS: 5. percentil – 3,9 ms/mmHg; 50. – 9,1; 95. – 18,7, a limity pro BRSf: 5. percentil – 8,5 mHz/mmHg; 50. – 16,4; 95. – 33,6. Závěr: Na SI závislá BRS byla v jednotlivých věkových podskupinách nezměněná, ale po standardizaci BRS na IBI byl prokázán pokles s věkem. BRSf, která byla na SI nezávislá, lépe odrážela vývoj citlivosti baroreflexu.
Links
| MSM0021622402, plan (intention) |
| ||
| NR8006, research and development project |
|