ZÁVODNÁ, Eva, Nataša HONZÍKOVÁ, Hana HRSTKOVÁ, Zuzana NOVÁKOVÁ, Jiří MOUDR, Miroslav JÍRA and Bohumil FIŠER. Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age? Canadian Journal of Physiology and Pharmacology. Ottawa, Canada: National Research Council of Canada, 2006, vol. 84, No 12, p. 1275-1283. ISSN 0008-4212. |
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@article{717576, author = {Závodná, Eva and Honzíková, Nataša and Hrstková, Hana and Nováková, Zuzana and Moudr, Jiří and Jíra, Miroslav and Fišer, Bohumil}, article_location = {Ottawa, Canada}, article_number = {12}, keywords = {baroreflex sensitivity; spectral analysis; age; adolescents; children}, language = {eng}, issn = {0008-4212}, journal = {Canadian Journal of Physiology and Pharmacology}, title = {Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age?}, url = {http://rparticle.web-p.cisti.nrc.ca/rparticle/AbstractTemplateServlet?journal=cjpp&volume=84&year=2006&issue=12&msno=y06-060&calyLang=eng}, volume = {84}, year = {2006} }
TY - JOUR ID - 717576 AU - Závodná, Eva - Honzíková, Nataša - Hrstková, Hana - Nováková, Zuzana - Moudr, Jiří - Jíra, Miroslav - Fišer, Bohumil PY - 2006 TI - Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age? JF - Canadian Journal of Physiology and Pharmacology VL - 84 IS - 12 SP - 1275-1283 EP - 1275-1283 PB - National Research Council of Canada SN - 00084212 KW - baroreflex sensitivity KW - spectral analysis KW - age KW - adolescents KW - children UR - http://rparticle.web-p.cisti.nrc.ca/rparticle/AbstractTemplateServlet?journal=cjpp&volume=84&year=2006&issue=12&msno=y06-060&calyLang=eng N2 - The aim of the study was to determine changes of baroreflex sensitivity (BRS/BRSf) in humans between 11 and 20 years of age. Beat-by-beat values of inter-beat intervals (IBI) or heart rate, and systolic and diastolic blood pressures were measured for 5 min in 415 healthy subjects. BRS did not correlate with age, but BRSf significantly decreased (p<0.001). BRS correlated with mean IBI (p<0.001), but BRSf was IBI-independent. Results of multiregression equations were: BRS=1.37-0.56*age+0.02*IBI (p<0.001 for BRS vs. age and for BRS vs. IBI); BRSf=34.74–0.97*age-0.001*IBI (p<0.001 only for BRS vs. age). The limits of BRS: 5th percentile - 3.9 ms/mmHg; 50th - 9.1; 95th - 18.7, and limits for BRSf: 5th percentile - 8.5 mHz/mmHg; 50th - 16.4; 95th - 33.6. Conclusion: IBI-dependent BRS was unchanged in the particular age groups, but the standardization of BRS on IBI was decreased with age. BRSf was IBI-independent and better reflected the development of the baroreflex sensitivity. ER -
ZÁVODNÁ, Eva, Nataša HONZÍKOVÁ, Hana HRSTKOVÁ, Zuzana NOVÁKOVÁ, Jiří MOUDR, Miroslav JÍRA and Bohumil FIŠER. Can we detect the development of baroreflex sensitivity in humans between 11 and 20 years of age? \textit{Canadian Journal of Physiology and Pharmacology}. Ottawa, Canada: National Research Council of Canada, 2006, vol.~84, No~12, p.~1275-1283. ISSN~0008-4212.
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