| HRSTKOVÁ, Hana, Lubomír ELBL, Iva TOMÁŠKOVÁ, Zuzana NOVÁKOVÁ, Nataša HONZÍKOVÁ, Bohumil FIŠER, Eva ZÁVODNÁ, Jana ŠŤASTNÁ and Klára KRONTORÁDOVÁ. EXERCISE TESTING IN CHILDREN AND ADOLESCENTS AFTER COMPLETING ANTHRACYCLINE ANTITUMOUR THERAPY. Scripta medica. Brno: Lékařská fakulta MU Brno, 2006, vol. 79, No 5, p. 249-255. ISSN 1211-3395. |
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@article{717593,
author = {Hrstková, Hana and Elbl, Lubomír and Tomášková, Iva and Nováková, Zuzana and Honzíková, Nataša and Fišer, Bohumil and Závodná, Eva and Šťastná, Jana and Krontorádová, Klára},
article_location = {Brno},
article_number = {5},
keywords = {Anthracyclines; Baroreflex sensitivity ; Exercise ; Cardiotoxicity},
language = {eng},
issn = {1211-3395},
journal = {Scripta medica},
title = {EXERCISE TESTING IN CHILDREN AND ADOLESCENTS AFTER COMPLETING ANTHRACYCLINE ANTITUMOUR THERAPY},
volume = {79},
year = {2006}
}
TY - JOUR
ID - 717593
AU - Hrstková, Hana - Elbl, Lubomír - Tomášková, Iva - Nováková, Zuzana - Honzíková, Nataša - Fišer, Bohumil - Závodná, Eva - Šťastná, Jana - Krontorádová, Klára
PY - 2006
TI - EXERCISE TESTING IN CHILDREN AND ADOLESCENTS AFTER COMPLETING ANTHRACYCLINE ANTITUMOUR THERAPY
JF - Scripta medica
VL - 79
IS - 5
SP - 249-255
EP - 249-255
PB - Lékařská fakulta MU Brno
SN - 12113395
KW - Anthracyclines
KW - Baroreflex sensitivity
KW - Exercise
KW - Cardiotoxicity
N2 - Analysis of cardiovascular parameters during bicycle ergometry in healthy children and adolescents and oncological patients after complete antitumor therapy was the aim of the present study. We studied 19 patients treated with anthracyclines for a malignant disease (acute lymphoblastic leukeamia), group A and 19 healthy children and adolescents, group C. Control subjects were randomly chosen from 60 healthy volunteers at the basic and secondary grammar schools in Brno age-matched 1:1. The test was carried out on the ergometer. We used a continuous exercise test with an increment of 25 Watts/2min until the exhaustion of the subjects. The baseline values of blood pressure and heart rate and the same values immediately at the end of the test together with standard testing parameters were analysed. Baroreflex sensitivity as index autonomous regulation of blood pressure was determined by spectral method. There were no differences between group A and C either in baseline parameters or in mean values in studied parameters during exercise testing. The distribution histograms of maximal tolerated load and maximal tolerated load per kg of body weight differed significantly (p<0.05, F-test). In spite of significant difference in distribution of tolerated load during exercise between treated patients and controls, the differences in mean values of all parameters were insignificant. This indicates that in majority of subjects after anthracycline treatment the load tolerance need not affected.
ER -
HRSTKOVÁ, Hana, Lubomír ELBL, Iva TOMÁŠKOVÁ, Zuzana NOVÁKOVÁ, Nataša HONZÍKOVÁ, Bohumil FIŠER, Eva ZÁVODNÁ, Jana ŠŤASTNÁ and Klára KRONTORÁDOVÁ. EXERCISE TESTING IN CHILDREN AND ADOLESCENTS AFTER COMPLETING ANTHRACYCLINE ANTITUMOUR THERAPY. \textit{Scripta medica}. Brno: Lékařská fakulta MU Brno, 2006, vol.~79, No~5, p.~249-255. ISSN~1211-3395.
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