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@inproceedings{717605, author = {Rázga, Filip and Koča, Jaroslav and Šponer, Jiří}, address = {Brno}, booktitle = {Strukturní biofyzika makromolekul II}, edition = {první}, keywords = {RNA flexibility; Molecular dynamics}, language = {eng}, location = {Brno}, pages = {14-14}, publisher = {Brno}, title = {Elastic properties of ribosomal RNA building blocks: Molecular dynamics study}, year = {2007} }
TY - JOUR ID - 717605 AU - Rázga, Filip - Koča, Jaroslav - Šponer, Jiří PY - 2007 TI - Elastic properties of ribosomal RNA building blocks: Molecular dynamics study PB - Brno CY - Brno KW - RNA flexibility KW - Molecular dynamics N2 - Explicit solvent Molecular Dynamics was used to describe the intrinsic flexibility of 23S rRNA Kink-turn motifs (e.g. Kt-38, Kt-42, Kt-58) and 23S rRNA Helix 42-44 (i.e. GTPase associated center rRNA with adjacent Kt-42). We demonstrate how rRNA building blocks with contrasting intrinsic flexibilities can form larger architectures with highly specific patterns of preferred low-energy motions and geometries. Additionally, the preferred low-energy motions of different rRNA motifs (e.g. 23S rRNA Kink-turn motifs, 23S rRNA Helix 42-44 (i.e. GTPase associated center rRNA), 23S rRNA Helix 90-92 (i.e. three-way-junction with A-loop), 23S Sarcin-ricin loop, 16S rRNA Helix 44 and 5S rRNA loop E) will be compared and discussed. ER -
RÁZGA, Filip, Jaroslav KOČA and Jiří ŠPONER. Elastic properties of ribosomal RNA building blocks: Molecular dynamics study. In \textit{Strukturní biofyzika makromolekul II}. první. Brno: Brno, 2007, p.~14-14.
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