| LEXA, Matej, Tomáš MARTÍNEK, Patrik BECK, Otto FUČÍK, Giorgio VALLE and Ivano ZARA. Genomic PCR simulation with hardware-accelerated approximate sequence matching. In Proceedings 21st European Conference on Modelling and Simulation. Praha: ECMS, 2007, p. 333-338. ISBN 978-0-9553018-2-7. |
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@inproceedings{718980,
author = {Lexa, Matej and Martínek, Tomáš and Beck, Patrik and Fučík, Otto and Valle, Giorgio and Zara, Ivano},
address = {Praha},
booktitle = {Proceedings 21st European Conference on Modelling and Simulation},
keywords = {Virtual PCR; FPGA; sequence alignment; mathematical model},
language = {eng},
location = {Praha},
isbn = {978-0-9553018-2-7},
pages = {333-338},
publisher = {ECMS},
title = {Genomic PCR simulation with hardware-accelerated approximate sequence matching},
year = {2007}
}
TY - JOUR
ID - 718980
AU - Lexa, Matej - Martínek, Tomáš - Beck, Patrik - Fučík, Otto - Valle, Giorgio - Zara, Ivano
PY - 2007
TI - Genomic PCR simulation with hardware-accelerated approximate sequence matching
PB - ECMS
CY - Praha
SN - 9780955301827
KW - Virtual PCR
KW - FPGA
KW - sequence alignment
KW - mathematical model
N2 - We report the latest details on improvements made or planned for the VPCR simulation software currently accessible on the Internet. We describe the inner workings of the dynamic amplification simulation model, concentrating mostly on the time- and sensitivity-critical step of sequence matching. Replacement of BLAST by the more sensitive and faster PRMEX similarity search program resulted in a marked improvement of PCR product predictions. Further speed improvements were acheived using hardware acceleration of approximate sequence matching.
ER -
LEXA, Matej, Tomáš MARTÍNEK, Patrik BECK, Otto FUČÍK, Giorgio VALLE and Ivano ZARA. Genomic PCR simulation with hardware-accelerated approximate sequence matching. In \textit{Proceedings 21st European Conference on Modelling and Simulation}. Praha: ECMS, 2007, p.~333-338. ISBN~978-0-9553018-2-7.
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