ŠMEJKAL, Karel, Lenka GRYCOVÁ, Radek MAREK, Filip LEMIERE, Dagmar JANKOVSKÁ, Hana FOREJTNÍKOVÁ, Ján VANČO and Václav SUCHÝ. C-Geranyl Compounds from <i>Paulownia tomentosa</i> Fruits. Journal of Natural Products. Washington: American Chemical Society, 2007, vol. 70, No 8, p. 1244-1248. ISSN 0163-3864. Available from: https://dx.doi.org/10.1021/np070063w.
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Basic information
Original name C-Geranyl Compounds from <i>Paulownia tomentosa</i> Fruits
Name in Czech C-Geranyl Compounds from <i>Paulownia tomentosa</i> Fruits
Authors ŠMEJKAL, Karel (203 Czech Republic), Lenka GRYCOVÁ (203 Czech Republic, belonging to the institution), Radek MAREK (203 Czech Republic, guarantor, belonging to the institution), Filip LEMIERE (56 Belgium), Dagmar JANKOVSKÁ (203 Czech Republic), Hana FOREJTNÍKOVÁ (203 Czech Republic), Ján VANČO (203 Czech Republic) and Václav SUCHÝ (203 Czech Republic).
Edition Journal of Natural Products, Washington, American Chemical Society, 2007, 0163-3864.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10406 Analytical chemistry
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
WWW DOI: 10.1021/np070063w
Impact factor Impact factor: 2.551
RIV identification code RIV/00216224:14310/07:00022177
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1021/np070063w
UT WoS 000248978800005
Keywords in English flavonoid; geranyl; natural product; NMR
Tags flavonoid, geranyl, natural product, NMR
Tags International impact, Reviewed
Changed by Changed by: prof. RNDr. Radek Marek, Ph.D., učo 381. Changed: 7/3/2015 09:17.
Abstract
Five geranylflavonoids, one prenylated flavonoid, and a simple flavanone were isolated from an ethanolic extract of Paulownia tomentosa fruit. Tomentodiplacol (1), 3-O-methyl-5-methoxydiplacol (2), 6-isopentenyl-3-O-methyltaxifolin (3), and dihydrotricin (4) are reported from a natural source for the first time and 3-O-methyldiplacone (6) for the first time from the genus Paulownia. The structures of the compounds were determined by mass spectrometry, including HR-MS, and by 1D and 2D NMR spectroscopy. The cytotoxicity and DPPH (2,2-diphenyl-1-picrylhydrazyl) quenching activity of some of these compounds were tested, with diplacone proving to be the best antioxidant, though the most cytotoxic compound.
Abstract (in Czech)
Five geranylflavonoids, one prenylated flavonoid, and a simple flavanone were isolated from an ethanolic extract of Paulownia tomentosa fruit. Tomentodiplacol (1), 3-O-methyl-5-methoxydiplacol (2), 6-isopentenyl-3-O-methyltaxifolin (3), and dihydrotricin (4) are reported from a natural source for the first time and 3-O-methyldiplacone (6) for the first time from the genus Paulownia. The structures of the compounds were determined by mass spectrometry, including HR-MS, and by 1D and 2D NMR spectroscopy. The cytotoxicity and DPPH (2,2-diphenyl-1-picrylhydrazyl) quenching activity of some of these compounds were tested, with diplacone proving to be the best antioxidant, though the most cytotoxic compound.
Links
LC06030, research and development projectName: Biomolekulární centrum
Investor: Ministry of Education, Youth and Sports of the CR, Biomolecular centre
MSM0021622413, plan (intention)Name: Proteiny v metabolismu a při interakci organismů s prostředím
Investor: Ministry of Education, Youth and Sports of the CR, Proteins in metabolism and interaction of organisms with the environment
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